2.6 Lundy Ch. 2 (4) Flashcards
PNS demyelination often results in
- disrupted proprioception
- weakness
Guillain-Barré
- antibodies attack Schwann cells
- usu 2-3 weeks after mild infection
Guillain-Barré s/s
- decreased sensation
- skeletal paralysis
- pain, hypersensitivity
- cranial nerves of face may be affected
Guillain-Barré course
- rapid onset
- plateau
- gradual recovery (usu complete)
severe cases of Guillain-Barré (recovery)
may have cardiorespiratory problems
Guillain-Barré treatments
- plasmapheresis
- IV immunoglobulin therapy
**remove or neutralize antibodies that are attacking the cells
PT for Guillain-Barré
- acute: ROM
- recovery: strengthening, functional mobility
CNS demyelination
damage to myelin sheaths in brain and spinal cord
MS
multiple sclerosis
What happens in MS?
immune system attacks oligodendrocytes, producing plaques
plaques
patches of demyelination
MS s/s
- weakness
- lack of coordination
- impaired vision
- impaired sensation
- slurred speech
MS age of onset
20-40
types of MS
- relapsing/remitting
- secondary progressive
- primary progressive
- progressive relapsing
Deficiency in this may result in greater likelihood of developing MS
vitamin D
MS more common in (men/women)
women
PT treatment of MS
- maintain and improve function when possible
- avoid high temp, excessive exertion
- regular exercise
- stress mgmt