2.1 Lecture notes Flashcards
two possible pathways for afferents
- spinal cord (via dorsal roots)
- solitary nucleus (via cranial nerve)
Where does referred pain come from?
- nociception from the viscera joins nociceptive axons and go to the somatosensory cortex
- all axons traveling together in the same group
Where does muscle guarding come from?
when somatic efferents join autonomic efferents
What parts of the brain make the decision on what to do with afferent information that’s received?
pons
medulla
Which cranial nerves are involved in taste?
VII
IX
X
Which cranial nerves are associated with abdominal and thoracic viscera
IX
X
Where is the solitary nucleus located?
medulla
Where does the adrenal medulla secrete epinephrine?
directly into the bloodstream
targets for sympathetic
- heart
- blood vessels
- bronchi
nicotinic receptors: where did the name come from?
- nicotine can bind and competitively inhibit ACh from binding
- activates the receptors
- sensitive to nicotine
Nicotinic receptors are always ______
ionotropic
sympathetic: What levels are the preganglionic nuclei in?
T1-L2
What are the levels in the parasympathetic system?
- cranial nerves III, VII, IX, X
- S2-S4
parasympathetic: preganglionic neuron releases
ACh (nicotinic, fast)
parasympathetic: postganglionic neuron releases
ACh (muscarinic, g-protein, slow)
targets for parasympathetic
- glands
- smooth muscle
- heart
- bronchioles
What happens when nicotine binds to receptors?
- fast effect
- feeling of alertness and calmness
Why is it so difficult for people to quit smoking?
- difficult for ACh to do its job
- don’t get continued stimulation of reward pathway
- nicotine also changes the shape of the synapse
What sort of effects are seen with muscarinic receptors?
slow responses (i.e. peristalsis, slowing down the system)
paravertebral ganglia
- where some of the preganglionic neurons synapse
- don’t have to
To get to the face and arteries of the upper limb, where must sympathetic fibers run?
through cervical paravertebral ganglia
sympathetic T5-T12 supplies
abdominal and viscera
sympathetic T1-T4 supplies
heart and lungs
sympathetic L1-L2 supplies
bowel, bladder, genitals, LE