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Pharmacology > synch session modules 7 and 10 > Flashcards

synch session modules 7 and 10 Flashcards

1
Q

meds that work at vascular smooth muscle

A 
hydralazine
minoxidil
nitroprusside
diazoside
CCB
thiazides
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2
Q

meds that work at vascular a1 receptors

A

prazosin
terazosin
labetalol

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3
Q

meds that work at renal tubules

A

thiazides
furosemides
K+ sparing diuretics

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4
Q

meds that work at brainstem

A

clonidine

methyldopa

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5
Q

meds that work at cardiac B1 receptors

A

propranolol
metoprolol
BB

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6
Q

meds that work at B1 receptors in juxtaglomerular cells

A

propranolol

metoprolol

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7
Q

meds that work on renin

A

aliskiren

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8
Q

meds that work on ACE

A

captropril

enalapril

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9
Q

meds that work at angiotensin 2 receptors

A

losartan

valsartan

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10
Q

meds that work at aldosterone receptors

A

spironolactone

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11
Q

first line HTN meds

A

thiazides
CCB: DHP
ACEI/ARB

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12
Q

drugs that cause hypokalemia

A

HCTZ

furosemide

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13
Q

drugs that cause hyperkalemia

A

spirolactone
aliskiren
lisinopril
lostartan

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14
Q

HF and verapamil

A

CCB verapamil has a negative inotropic effect, will worsen HF s/s

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15
Q

drugs that reduce preload

A

diuretics
aldosterone antagonists
venodialtors

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16
Q

drugs that reduce afterload

A

ACEI
BB
vasodilators

17
Q

drugs that increase inotropy

A

digoxin
catecholamines
phosphodiasterase inhibitors

18
Q

digoxin mechanism of action

A

inhibits Na/K exchange by Na/K ATPase

  • > inc. of intracelluar Na -> dec. concentration gradient across membrane
  • inc. Na dec. the driving force for the Na/Ca exchanger
  • > dec. ca into extracellular space
19
Q

digoxin and inotropy

A

positive effect

20
Q

drugs with negative inotropic effect

A

BB
CCB
antiarrhythmic meds

21
Q

ezetimibe works at what site

A

small intestine

- dec. cholesterol absorption

Pharmacology (78 decks)

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