module 16 non-insulin meds 2

Question 1

SGLT-2 inhibitor meds

Answer 1

canagliflozin
dapagliflozin
empagliflozin
ertugliflozin

Question 2

SGLT-2 inhibitor MOA

Answer 2

inhibits SGLT-2 transporter in kidney

-> dec. glucose reabsorption, inc. glucose excretion

Question 3

SGLT-2 inhibitor AE

Answer 3

genital UTI/fungal infection
- (inc. sugar in tubules)
dizzy
hypotension
inc. K (renal impairment)
AKI
rare: Fournier's gangrene

Question 4

SGLT-2 inhibitor CI

Answer 4

CrCl < 45mL/min

Question 5

SGLT-2 inhibitor labs

Answer 5

creatinine

Question 6

SGLT-2 inhibitor EDU

Answer 6

wt. loss

cardio benefit

Question 7

alpha-glucosidase inhibitor meds

Answer 7

acarbose

meglitol

Question 8

alpha-glucosidase inhibitor MOA

Answer 8

acts in intestine to delay carbohydrate absorption

- inhibits enzymes like sucrose and maltase

Question 9

alpha-glucosidase inhibitor AE

Answer 9

flatulence
diarrhea
low risk hypoglycemia

Question 10

alpha-glucosidase inhibitor EDU

Answer 10

with meals

frequent dosing

Question 11

alpha-glucosidase inhibitor EDU

Answer 11

weight neutral

Question 12

Amylin analog med

Answer 12

pramlintide

Question 13

pramlintide MOA

Answer 13

mimics amylin

- dec. gastric emptying, regulates post-prandial glucagon, dec. food intake

Question 14

pramlintide AE

Answer 14

N/V

low risk hypoglycemia

Question 15

pramlintide admin

Answer 15

injectable

immediately before meals

Question 16

pramlintide EDU

Answer 16

wt. loss

limited place in therapy

Question 17

amylin

Answer 17

hormone co-secreted with insulin by B-cells in the pancreas

regulated circulating nutrient levels