module 6 adrenoreceptor antagonist

Question 1

a-antagonist

Answer 1

a-receptor responds faster than B-receptor

blocks stimulatory effects of norepi on a-receptor

Question 2

a-antagonist cardiovascular effects

Answer 2

A1:
- dec. PVR and dec. BP
- postural hypoTN d/t failure of vasoconstriction upon standing
A2:
- inc. norepi release from nerve terminals

Question 3

a-antagonist GU effects

Answer 3

blockade in prostate and bladder -> muscle relaxation and ease micturation

inc. nasal stuffiness
miosis: pupil constriction

Question 4

B- antagonist cardiovascular effects

Answer 4

dec. CO -> dec. BP

inc. Na retention

Question 5

B-antagonist respiratory effects

Answer 5

inc. airway resistance

Question 6

B-antagonist Ocular effects

Answer 6

dec. aqueous humor production

Question 7

B-antagonist metabolic effects

Answer 7

dec. carb metabolism, dec. insulin release
dec. renin secretion -> dec. angiotensin
dec. Na excretion
dec. lipolysis

Question 8

COMT

Answer 8

breaks down catecholamines

Question 9

B-1 agonism

Answer 9

inc. force and rate of heart contraction

Question 10

B-2 agonism

Answer 10

smooth muscle relaxation: resp. vascular, uterine

Question 11

B- antagonism

Answer 11

dec. production of aqueous humor
bronchoconstriction
dec. HR, contractility, and BP

Question 12

DA agonism

Answer 12

renal vasodilation

modulates NT release

Question 13

DA antagonism

Answer 13

atypical antipsychotics