module 14 uterotonics Flashcards
1
Q
uterotonic meds
A
oxytocin
dinoprostone
misoprostol
2
Q
oxytocin MOA
A
inc. myometrial contraction by inc. free intracellular Ca
3
Q
oxytocin use
A
induce/augment labor contract mammary glands: milk letdown stimulate uterus contractions - labor, termination of pregnancy - stop bleeding: postpartum - subinvolution: dec. uterus to normal size after birth
4
Q
oxytocin admin
A
Continuous IV drip - destroyed in GI does not cross BBB half-life: <6 min effect: lasts 2-3 hours
5
Q
oxytocin EDU
A
weak antidiuretic d/t ADH like effect
6
Q
dinoprostone MOA
A
naturally occurring PGE2
sensitizes myometrium to oxytocin
7
Q
dinoprostone use
A
cervical ripening
8
Q
dinoprostone admin
A
vaginal insert
cervical gel
9
Q
misoprostol MOA
A
synthetic PGE1
10
Q
misoprostol use
A
cervical ripening
labor induction
postpartum hemorrhage
11
Q
misoprostol AE
A
oral: pregnancy category X when used as GI agent.
