module 5 stimulant abuse

Question 1

stimulants

Answer 1

cocaine
amphetamines
- produce feelings of well-being, energy, and optimism
- can cause agitation, paranoia, and psychosis

Question 2

cocaine MOA

Answer 2

inhibits dopamine reuptake -> inc. dopamine levels at synapses, and postsynaptic receptors activated.

Question 3

cocaine and tolerance

Answer 3

• over time dopamine stores are depleted

- fewer dopamine receptors (down-regulation)

Question 4

cocaine withdrawal

Answer 4

causes dec. dopamine levels at synapses

Question 5

amphetamine MOA

Answer 5

releases stored dopamine into synapses and prevents re-uptake into vesicles
-> inc. dopamine at synaptic cleft

Question 6

cocaine withdrawal s/s

Answer 6

within 90 minutes, last 7-10 days 
bradycardia
sleepy
fatigue
nausea
vomiting
dysphoria
anhedonia (inability to feel pleasure)

Question 7

amphetamine withdrawal s/s

Answer 7

lasts 5-7 days
anhedonia (inability to feel pleasure)
dec. concentration
depression
HA
irritability
suicidal thoughts

Question 8

MDMA MOA

Answer 8

street names: ecstasy, molly

inc. serotonin in the extracellular space while depleting presynaptic dopamine stores

Question 9

MDMA drug class

Answer 9

phenylethylamine hallucinogenics

- chemically related to methamphetamine

Question 10

MDMA withdrawal s/s

Answer 10

agitation 
anxiety
depression 
insomnia
paranoia

Question 11

nonpharm stimulat withdrawal management

Answer 11

psychotherapy
support groups
inpatient detox