RNA Viruses Flashcards

1
Q

What is the #1 RNA virus that causes a cold?

A

Rhinovirus

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2
Q

What is the #1 RNA virus that causes childhood pneumonia?

A

Respiratory Syncytial Virus (RSV)

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3
Q

What cells are formed with Respiratory Syncytial Virus (RSV)?

A

Giant cells

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4
Q

What does Metapneumovirus cause in children?

A

Pneumonia

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5
Q

What does Parainfluenza cause?

A

Croup with infection of the larynx/bronchus

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6
Q

“barking cough” is seen with what virus?

A

Parainfluenza

– Causes croup and infection of larynx/bronchus

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7
Q

Coronavirus causes?

A

Colds and Atypical pneumonia

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8
Q

SARS

A

Severe Acute Respiratory Syndrome

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9
Q

What are 5 respiratory viruses?

A
Rhinovirus
Respiratory Syncytial Virus (RSV)
Metapneumovirus
Parainfluenza
Coronavirus
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10
Q

Influenza has 2 ____ virulence factors

A

Glycoprotein

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11
Q

What are the virulence factors for Influenza?

A
  1. Hemagglutinin

2. Neuraminidase

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12
Q

What are the virulence factors for Influenza?

A
  1. Hemagglutinin

2. Neuraminidase

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13
Q

Action of Hemagglutinin?

A
  • Virulence factor of Influenza

= Binds to sialic acid receptors

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14
Q

Action of Neuraminidase?

A
  • Virulence factor of Influenza

= Disrupts mucin barrier

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15
Q

Symptoms of Influenza infection?

A

Fever, rhinorrhea, cough, myalgias

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16
Q

Antigenic Drift

A

Mutations that result in small changes in Hemagluttinin and Neuraminidase

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17
Q

What type of disease does Antigenic Drift cause and why?

A

Milder infection because the previous antibodies still partially recognize the modified Hemagluttinin and Neuraminidase

18
Q

Antigenic Shift

A

Trading of RNA segments between viruses resulting in completely NEW hemagluttinin and Neuraminidase

19
Q

What type of disease does Antigenic Shift cause and why?

A

Everyone is susceptible because it creates completely new virulence factors

20
Q

MMR vaccine protects against?

A

Measles
Mumps
Rubella

21
Q

Cascade of symptoms of Measles infection?

A
  • Fever and cough
  • Koplik’s spots
  • Head to toe maculopapular rash
    • Possible pneumonia
22
Q

Koplik’s spots?

A

Oral lesions that are white and red on the periphery

- seen with Measles

23
Q

Main symptoms of Measles?

A
  • Koplik’s spots (white oral lesions with red periphery)

- Head to toe maculopapular rash

24
Q

What is Subacute Sclerosing Panencephalitis?

A

Progressive neurologic disease
= forgetfullness, hallucinations and distractibility
– later symptom of measles infection

25
Q

When will those with measles develop subacute sclerosing panencephalitis?

A

Months to years after the initial infection

26
Q

Rubella symptoms are very similar to?

A

Measles

- fever, cough, head to toe rash

27
Q

When is Rubella dangeorus?

A

When it crosses the placenta

= Cataracts, heart and CNS damage

28
Q

What does Rubella cause to result if it crosses the placenta?

A

Cataracts, heart and CNS defects

29
Q

______ from inoculation Mumps spreads into the bloodstream

A

3 weeks

30
Q

Symptoms of Mumps infection?

A

Fever

Pain and swelling of Parotid gland and Testicles

31
Q

Pain and swelling of parotid gland and testicles with a fever is seen with?

A

Mumps

32
Q

What 2 diseases can Coxsackie Virus A cause?

A

Herpangina

Hand, foot and mouth disease

33
Q

Herpangina

A
  • Caused by Coxsackie Virus A

= BILATERAL vesicular eruption in back of throat

34
Q

Bilateral vesicular eruption in the back of the throat

A

Herpangina

- caused by Coxsackie Virus A

35
Q

Hand, Foot and Mouth disease

A
  • Caused by Coxsackie Virus A

= red lesions of the hand, foot and mouth

36
Q

What sheds Hantavirus?

A

Rodents

37
Q

Where is Hantavirus common?

A

Southwest U.S

38
Q

Hantavirus causes what symptoms?

A

Flu-like

39
Q

What syndrome can Hantavirus progress to?

A

Hantavirus Pulmonary Syndrome

40
Q

Hantavirus Pulmonary Syndrome?

A

Fluid leakage in pulmonary capillaries that leads to shock and death
- due to hantavirus