DNA Viruses (cont.) Flashcards
What are the DNA viruses?
HHAPPPy
- Herpesvirus
- Hepadnavirus
- Adenovirus
- Papovavirus
- Parvovirus
- Poxvirus
What does Adenovirus cause?
A cold
- sore throat, rhinorrhea, cough, malaise
DNA virus that causes a cold?
Adenovirus
3 Papovaviruses?
Human Papilloma Virus (HPV)
BK Polyoma Virus
JC Polyoma Virus
3 Papovaviruses?
Human Papilloma Virus (HPV)
BK Polyoma Virus
JC Polyoma Virus
What does the Human Papilloma Virus cause?
Common and genital warts
What proteins in the Human Papilloma Virus interfere with the tumor suppressor genes?
E6 and E7
If E6 and E7 proteins with Human Papilloma Virus interfere with tumor suppressor genes, what will that cause?
Epithelial Dysplasia
What can Epithelial Dysplasia result in?
Carcinoma
What are the high risk strains that can cause cervical cancer from the Human Papilloma Virus?
16, 18, 31, 45
What test catches cervical cancer from Human Papilloma Virus at the dysplasia/carcinoma stage?
Pap smear
In what patient population can BK and JC Polyomavirus cause disease?
Immunocompromised
BK polyomavirus causes disease in ____ patients
Renal transplant
Symptoms of BK Polyomavirus infection?
Ground glass inclusions in the bladder and kidney
JC Polyomavirus causes disease ___ patients
AIDS
Symptoms of JC Polyomavirus infection?
Progressive Multifocal Leukoencephalopathy
= Demyelinating CNS
== Speech, behavior, motor problems
Parvovirus B19 causes what main symptoms in a child?
Rash slapped cheeks (erythema infectiosum), low fever, headache
Rash slapped cheeks
Parvovirus B19
If Parvovirus B19 causes a transient aplastic crisis what does the virus do?
Infects RBC precursors (reticulocytes)
A transient aplastic crisis due to parvovirus B19 that is temporary causes?
Decrease in RBC production that will return to normal
A transient aplastic crisis due to parvovirus B19 in child with sickle cell or thalassemia will cause?
Severe anemia, fetal hydrops and death
What are the Poxvirus members?
Molluscum Contagiosum
Smallpox
Molluscum Contagiosum and Smallpox are members of what virus?
Poxvirus
Who is at risk for infection with Molluscum Contagiosum?
Children and HIV patients
Symptoms of infection with Molluscum Contagiosum?
Dome lesions with center dimple all over the body
Symptoms of infection with Smallpox?
Fever and hard vesicles all in same stage of development
Hard vesicles all in the same stage of development
Smallpox
