DNA Viruses (cont.) Flashcards

1
Q

What are the DNA viruses?

A

HHAPPPy

  • Herpesvirus
  • Hepadnavirus
  • Adenovirus
  • Papovavirus
  • Parvovirus
  • Poxvirus
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2
Q

What does Adenovirus cause?

A

A cold

- sore throat, rhinorrhea, cough, malaise

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3
Q

DNA virus that causes a cold?

A

Adenovirus

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4
Q

3 Papovaviruses?

A

Human Papilloma Virus (HPV)
BK Polyoma Virus
JC Polyoma Virus

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5
Q

3 Papovaviruses?

A

Human Papilloma Virus (HPV)
BK Polyoma Virus
JC Polyoma Virus

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6
Q

What does the Human Papilloma Virus cause?

A

Common and genital warts

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7
Q

What proteins in the Human Papilloma Virus interfere with the tumor suppressor genes?

A

E6 and E7

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8
Q

If E6 and E7 proteins with Human Papilloma Virus interfere with tumor suppressor genes, what will that cause?

A

Epithelial Dysplasia

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9
Q

What can Epithelial Dysplasia result in?

A

Carcinoma

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10
Q

What are the high risk strains that can cause cervical cancer from the Human Papilloma Virus?

A

16, 18, 31, 45

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11
Q

What test catches cervical cancer from Human Papilloma Virus at the dysplasia/carcinoma stage?

A

Pap smear

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12
Q

In what patient population can BK and JC Polyomavirus cause disease?

A

Immunocompromised

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13
Q

BK polyomavirus causes disease in ____ patients

A

Renal transplant

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14
Q

Symptoms of BK Polyomavirus infection?

A

Ground glass inclusions in the bladder and kidney

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15
Q

JC Polyomavirus causes disease ___ patients

A

AIDS

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16
Q

Symptoms of JC Polyomavirus infection?

A

Progressive Multifocal Leukoencephalopathy
= Demyelinating CNS
== Speech, behavior, motor problems

17
Q

Parvovirus B19 causes what main symptoms in a child?

A

Rash slapped cheeks (erythema infectiosum), low fever, headache

18
Q

Rash slapped cheeks

A

Parvovirus B19

19
Q

If Parvovirus B19 causes a transient aplastic crisis what does the virus do?

A

Infects RBC precursors (reticulocytes)

20
Q

A transient aplastic crisis due to parvovirus B19 that is temporary causes?

A

Decrease in RBC production that will return to normal

21
Q

A transient aplastic crisis due to parvovirus B19 in child with sickle cell or thalassemia will cause?

A

Severe anemia, fetal hydrops and death

22
Q

What are the Poxvirus members?

A

Molluscum Contagiosum

Smallpox

23
Q

Molluscum Contagiosum and Smallpox are members of what virus?

A

Poxvirus

24
Q

Who is at risk for infection with Molluscum Contagiosum?

A

Children and HIV patients

25
Q

Symptoms of infection with Molluscum Contagiosum?

A

Dome lesions with center dimple all over the body

26
Q

Symptoms of infection with Smallpox?

A

Fever and hard vesicles all in same stage of development

27
Q

Hard vesicles all in the same stage of development

A

Smallpox