Erythropoiesis Flashcards
Erythropoiesis forms?
RBCs (erythrocytes)
What 2 forms of elements in erythropoiesis are interchangeable?
- normoblast
- erythroblast
What is the first cell formed?
Pronormoblast/Proerythroblast
Attributes of Pronormoblast/Proerythroblast?
Large central nucleus with 3-5 pale nucleoli
What cell in erythropoiesis makes hemoglobin?
Pronormoblast/Proerythroblast
A Pronormoblast/Proerythroblast turns into?
Basophilic normoblast/erythroblast
A Pronormoblast/Proerythroblast turns into?
Basophilic normoblast/erythroblast
Attributes of Basophilic normoblast/erythroblast?
Patchy chromatin
Bluish (basophilic) cytoplasm
Attributes of Basophilic normoblast/erythroblast?
Patchy chromatin
Bluish (basophilic) cytoplasm
A Basophilic normoblast/erythroblast turns into?
Polychromatic normoblast/erythroblast
A Basophilic normoblast/erythroblast turns into?
Polychromatic normoblast/erythroblast
Attributes of Polychromatic normoblast/erythroblast?
Checkerboard condensed chromatin
Yellow-pink-blue cytoplasm
NO nucleoli
Attributes of Polychromatic normoblast/erythroblast?
Checkerboard condensed chromatin
Yellow-pink-blue cytoplasm
NO nucleoli
A Polychromatic normoblast/erythoblast turns into?
Orthochromic normoblast/erythroblast
A Polychromatic normoblast/erythroblast turns into?
Orthochromic normoblast/erythroblast
Attributes of orthochromic normoblast/erythroblast?
Eccentric Pyknotic nucleus
Pink cytoplasm
Attributes of orthochromic normoblast/erythroblast?
Eccentric Pyknotic nucleus
Pink cytoplasm
An Orthochromic normoblast/erythroblast turns into?
Reticulocyte
An Orthochromic normoblast/erythroblast turns into?
Reticulocyte
Another name for reticulocyte?
Polychromatic erythrocyte
Attributes of reticulocyte?
NO nucleus
BLUE staining ribosomes
Attributes of reticulocyte?
NO nucleus
BLUE staining ribosomes
A reticulocyte turns into?
Mature erythrocyte
A reticulocyte turns into?
Mature erythrocyte
If there is an increased number of reticulocytes in the blood, what could that indicate?
Hemolytic anemias!!
In hemolytic anemias, what cell type might be increased in peripheral blood?
Reticulocytes
What dye helps see the ribosomes in reticulocytes?
Supravital dye (blue)
Overall cascade of erythopoiesis?
Proerythroblast Basophilic erythroblast Polychromatic erythroblast Orthochromic erythroblast Reticulocyte Erythrocyte
Overall cascade of erythropoiesis?
Proerythroblast Basophilic erythroblast Polychromatic erythrobalst Orthochromic erythroblast Reticulocyte Erythrocyte
Overall cascade of erythropoiesis?
Proerythroblast Basophilic erythroblast Polychromatic erythroblast Orthochromic erythroblast Reticulocyte Erythrocyte
