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MOD > DNA Virus - Herpesvirus > Flashcards

DNA Virus - Herpesvirus Flashcards

1
Q

A virus is an infectious agent that contain?

A

Either DNA or RNA

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2
Q

Viruses require what type of cells?

A

Living cells for energy

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3
Q

Viruses - intracellular or extracellular?

A

Intracellular

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4
Q

How big are viruses?

A

TINY

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5
Q

What are the DNA Viruses?

A

HHAPPPy

  • Herpesvirus
  • Hepadnavirus
  • Adenovirus
  • Papovavirus
  • Parvovirus
  • Poxvirus
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6
Q

What are the DNA Viruses?

A

HHAPPPy

  • Herpesvirus
  • Hepadnavirus
  • Adenovirus
  • Papovavirus
  • Parvovirus
  • Poxvirus
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7
Q

What are the DNA Viruses?

A

HHAPPPy

  • Herpesvirus
  • Hepadnavirus
  • Adenovirus
  • Papovavirus
  • Parvovirus
  • Poxvirus
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8
Q

What are the main Herpesviruses?

A 
Herpes Simplex Viruses 1 and 2
Varicella - Zoster Virus
Epstein - Barr Virus
Cytomegalovirus
Roseola (HHV-6)
HHV-8
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9
Q

How are Herpes Simplex Viruses 1 and 2 spread?

A

Skin-to-skin contact

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10
Q

Herpes Simplex Virus (HSV) 1 involves what part of the body?

A

Orofacial

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11
Q

Herpes Simplex Virus (HSV) 2 involves what part of the body?

A

Genital

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12
Q

What are common orofacial and finger infections seen with Herpes Simplex Virus?

A 
Gingivostomatitis (orofacial involvement)
Herpetic Whitlow (finger infection)
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13
Q

Herpes Simplex Viruses 1 and 2 are causes of neonatal infection/death and are a part of the?

A

TORCH

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14
Q

What is the number 1 cause of encephalitis (inflammation of the brain)?

A

Herpes Simplex Virus

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15
Q

2 diseases caused by the Varicella-Zoster Virus?

A

Chickenpox (Varicella)

Shingles (Herpes Zoster)

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16
Q

The Varicella portion of the Varicella-Zoster Virus affects who how?

A

Children

- Aerosolized transmission and skin-to-skin transmission

17
Q

How long is the incubation period for the Varicella portion of the Varicella-Zoster Virus?

A

2 weeks

18
Q

Symptoms of Chickenpox (Varicella)?

A

Rash: Papules -> Vesicles -> Scabs

Fever, malaise

19
Q

How does one get Shingles (Herpes Zoster)?

A

Reactivation of latent infection in the DRG

20
Q

Symptoms of Shingles (Herpes Zoster)?

A

Painful, burning lesion in dermatomal distribution

21
Q

What determines where the lesion will be with Shingles (Herpes Zoster)?

A

Dermatome!

22
Q

How is Epstein-Barr Virus spread?

A

Saliva, toothbrushes, kissing, utensils

23
Q

What population and cells does the Epstein - Barr Virus affect?

A

Young adults

- AFFECTS B CELLS

24
Q

Via ____ receptor, Epstein - Barr virus affects B cells directly

A

C3d

25
Q

What does the Epstein - Barr virus cause and what are the symptoms?

A

Sore throat
Fever
Lymphadenopathy
Hepatosplenomegaly

26
Q

What cancers are those with the Epstein - Barr virus at risk for?

A

B cell lymphomas

Nasopharyngeal carcinomas

27
Q

How do lymphocytes look with Epstein - Barr virus?

A

Atypical - MORE cytoplasm

28
Q

What tests and when do you do them for the Epstein - Barr virus?

A

Heterophile Ab test (monospot)
– IF NEGATIVE –
EBV Ab test

29
Q

With Cytomegalovirus, most are?

A

Asymptomatic

30
Q

CMV Mononucleosis

A

Symptoms similar to EBV mononucleosis + GREATER FEVER!!!

- caused by cytomegalovirus

31
Q

What is caused in the immunocompromised if cytomegalovirus is reactivated?

A

Chorioretinitis

= Blurry vision and floaters

32
Q

Cytomegalovirus is a ____ disease because it causes congenital intellectual disability

A

TORCH

33
Q

HHV - 6

A

Roseola

34
Q

In what age group and what are the symptoms of Roseola (HHV-6)?

A

In children

= 3-5 days of high fever -> resolves -> RASH

35
Q

3-5 days of high fever -> resolves -> RASH

A

Roseola (HHV-6)

36
Q

What does HHV-8 cause?

A

Kaposi - Sarcoma

= vascular tumor

37
Q

Symptoms of Kaposi - Sarcoma?

A

Red/purple skin nodules

– caused by HHV-8

38
Q

In what populations is Kaposi - Sarcoma common?

A
  • Caused by HHV - 8

= Males with AIDS, in middle east and Africa

MOD (68 decks)

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