Gram (-) Bacteria - Enterics Flashcards
What enteric is a lactose fermenter and a normal part of the GI flora?
Escherichia Coli (E. Coli)
What does Escherichia Coli have that allows it to adhere to host cells?
Pili
Overall, what 4 diseases does Escherichia Coli cause?
Diarrhea
UTI
Neonatal Meningitis
Pneumonia
1 cause of a UTI?
Escherichia Coli
3 specific strains of Escherichia Coli that can cause diarrheal illnesses?
ETEC
EIEC
EHEC
What toxins are associated with ETEC strain of Escherichia Coli?
Heat labile and Heat stabile toxins
What type of diarrhea does the ETEC strain of Escherichia Coli cause?
Watery diarrhea
EIEC strain of Escherichia Coli contains?
Invasive plasmid
What type of diarrhea does the EIEC strain of Escherichia Coli cause?
Bloody diarrhea
What toxin is associated with the EHEC strain of Escherichia Coli?
Shiga - like toxin 1 and 2
What type of diarrhea does the EHEC strain of Escherichia Coli cause?
Bloody diarrhea
ETEC, EIEC, EHEC diarrhea types
ETEC - watery
EIEC, EHEC - bloody
What strain of Escherichia Coli is Hemolytic Uremic Syndrome (HUS) caused by?
EHEC 0157
Symptoms of Hemolytic Uremic Syndrome (HUS) due to EHEC?
Anemia
Thrombocytopenia
Renal failure
Shigella is what shape?
Rod
Most common shigella in the U.S?
S. Sonnei
What is the toxin produced with shigella?
Shiga toxin
Action of Shiga toxin?
Inhibits 60S ribosomal subunit and thus, protein synthesis = cell death
Inhibits 60S ribosomal subunit and thus, protein synthesis = cell death
Shiga toxin
What strain of shigella produces shiga toxin?
S. Dysenteriae
Symptoms with Shigella infection?
Fever and bloody diarrhea
Salmonella Typhi causes?
Typhoid Fever
What causes Typhoid fever?
Salmonella Typhi
“Typhoid Mary”
ASYMPTOMATIC carrier of Salmonella Typhi
Symptoms of Typhoid Fever due to salmonella typhi?
Stepwise fever - rises during day and drops in morning
RUQ pain and rose spots on abdomen
Delirium when fever peaks
Gallbladder issues
What type of salmonella is found in virtually all animals?
Non-typhoidal salmonella
Symptoms of infection due to non-typhoidal salmonella?
Gastroenteritis and 1/2 will get a fever
Symptoms of Typhoid Fever due to salmonella typhi?
Stepwise fever - rises during day and drops in morning
RUQ pain and rose spots on abdomen
Delirium when fever peaks
Gallbladder issues
What is a common source of Yersinia Enterocolitica?
Milk products
Symptoms of infection with Yersinia Enterocolitica?
Pseudoappendicitis, fever, diarrhea
What bacteria commonly mimics appendicitis?
Yersinia Enterocolitica
What bacteria has a swarming growth pattern of concentric rings?
Proteus Mirabilis
Proteus Mirabilis growth pattern?
Swarming concentric rings
Proteus Mirabilis is ____ (+)
Urease (+)
Job of urease?
Breaks down urea into CO2 and ammonia
What color will the urine turn in the lab with urease (+)
Pink
Proteus Mirabilis is a common cause of?
UTI in nosocomial setting
What population is at higher risk for infection with Klebsiella Pneumoniae?
Alcoholics and Hospitalized patients
Symptoms of Klebsiella Pneumoniae?
Necrotizing pneumonia with currant jelly sputum
What type of disease is associated with Klebsiella Pneumoniae?
Necrotizing pneumonia with currant JELLY sputum
