Gram (-) Bacteria - Enterics Flashcards

1
Q

What enteric is a lactose fermenter and a normal part of the GI flora?

A

Escherichia Coli (E. Coli)

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2
Q

What does Escherichia Coli have that allows it to adhere to host cells?

A

Pili

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3
Q

Overall, what 4 diseases does Escherichia Coli cause?

A

Diarrhea
UTI
Neonatal Meningitis
Pneumonia

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4
Q

1 cause of a UTI?

A

Escherichia Coli

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5
Q

3 specific strains of Escherichia Coli that can cause diarrheal illnesses?

A

ETEC
EIEC
EHEC

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6
Q

What toxins are associated with ETEC strain of Escherichia Coli?

A

Heat labile and Heat stabile toxins

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7
Q

What type of diarrhea does the ETEC strain of Escherichia Coli cause?

A

Watery diarrhea

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8
Q

EIEC strain of Escherichia Coli contains?

A

Invasive plasmid

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9
Q

What type of diarrhea does the EIEC strain of Escherichia Coli cause?

A

Bloody diarrhea

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10
Q

What toxin is associated with the EHEC strain of Escherichia Coli?

A

Shiga - like toxin 1 and 2

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11
Q

What type of diarrhea does the EHEC strain of Escherichia Coli cause?

A

Bloody diarrhea

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12
Q

ETEC, EIEC, EHEC diarrhea types

A

ETEC - watery

EIEC, EHEC - bloody

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13
Q

What strain of Escherichia Coli is Hemolytic Uremic Syndrome (HUS) caused by?

A

EHEC 0157

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14
Q

Symptoms of Hemolytic Uremic Syndrome (HUS) due to EHEC?

A

Anemia
Thrombocytopenia
Renal failure

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15
Q

Shigella is what shape?

A

Rod

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16
Q

Most common shigella in the U.S?

A

S. Sonnei

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17
Q

What is the toxin produced with shigella?

A

Shiga toxin

18
Q

Action of Shiga toxin?

A

Inhibits 60S ribosomal subunit and thus, protein synthesis = cell death

19
Q

Inhibits 60S ribosomal subunit and thus, protein synthesis = cell death

A

Shiga toxin

20
Q

What strain of shigella produces shiga toxin?

A

S. Dysenteriae

21
Q

Symptoms with Shigella infection?

A

Fever and bloody diarrhea

22
Q

Salmonella Typhi causes?

A

Typhoid Fever

23
Q

What causes Typhoid fever?

A

Salmonella Typhi

24
Q

“Typhoid Mary”

A

ASYMPTOMATIC carrier of Salmonella Typhi

25
Q

Symptoms of Typhoid Fever due to salmonella typhi?

A

Stepwise fever - rises during day and drops in morning
RUQ pain and rose spots on abdomen
Delirium when fever peaks
Gallbladder issues

26
Q

What type of salmonella is found in virtually all animals?

A

Non-typhoidal salmonella

27
Q

Symptoms of infection due to non-typhoidal salmonella?

A

Gastroenteritis and 1/2 will get a fever

28
Q

Symptoms of Typhoid Fever due to salmonella typhi?

A

Stepwise fever - rises during day and drops in morning
RUQ pain and rose spots on abdomen
Delirium when fever peaks
Gallbladder issues

29
Q

What is a common source of Yersinia Enterocolitica?

A

Milk products

30
Q

Symptoms of infection with Yersinia Enterocolitica?

A

Pseudoappendicitis, fever, diarrhea

31
Q

What bacteria commonly mimics appendicitis?

A

Yersinia Enterocolitica

32
Q

What bacteria has a swarming growth pattern of concentric rings?

A

Proteus Mirabilis

33
Q

Proteus Mirabilis growth pattern?

A

Swarming concentric rings

34
Q

Proteus Mirabilis is ____ (+)

A

Urease (+)

35
Q

Job of urease?

A

Breaks down urea into CO2 and ammonia

36
Q

What color will the urine turn in the lab with urease (+)

A

Pink

37
Q

Proteus Mirabilis is a common cause of?

A

UTI in nosocomial setting

38
Q

What population is at higher risk for infection with Klebsiella Pneumoniae?

A

Alcoholics and Hospitalized patients

39
Q

Symptoms of Klebsiella Pneumoniae?

A

Necrotizing pneumonia with currant jelly sputum

40
Q

What type of disease is associated with Klebsiella Pneumoniae?

A

Necrotizing pneumonia with currant JELLY sputum