Nutritional Diseases (9) Flashcards
Primary Nutrition
1 or all things are missing from diet
Secondary Nutrition
Malabsorption or impaired storage
Severe Acute Malnutrition is due to?
Inadequate intake of proteins and calories
Marasmus
Lack of calories
Physical exam findings with Marasmus?
Muscle loss, emaciated extremities that creates a LARGE head appearance
Kwashiorkor
Lack of proteins
Physical exam findings with Kwashiorkor?
Edema, pot belly, areas of hyperpigmentation of the skin
Marasmus affects _____ proteins while Kwashiorkor affects ____ proteins
Somatic
Visceral
Cachexia
Extreme weight loss and atrophy
What can cause cachexia?
Cancers, AIDS - die from respiration muscle loss
Anorexia Nervosa
Self-induced starvation and weight loss
What pathologic finding will be seen with Anorexia Nervosa?
Gelatinous transformation of bone marrow - FAT present!
Excess fat present in bone marrow smears suggests?
Anorexia Nervosa
Bulimia
Food purging via vomiting or diarrhea using laxitives
What 2 things are both Anorexia Nervosa and Bulimia susceptible to?
Cardiac Arrhythmias
Hypokalemia
Fat soluble vitamins?
ADEK
Function of Vitamin A?
Maintenance of vision
Deficiency of Vitamin A will cause?
- Night blindness
- Bitot spots
- Epithelial/squamous metaplasia of pulmonary epithelia
Vitamin A deficiency causes epithelial to squamous metaplasia of pulmonary epithelium. This increases the presence of?
Infections
Xeropthalmia
Dry eye
- Vitamin A deficient
Bitot spots are made of?
Keratin
- Vitamin A deficient
Toxicity of Vitamin A will result in?
Pseudotumor cerebri = Increased intracranial pressure
– headache, dizziness
Function of Vitamin D?
Maintenance of Calcium and Phosphorus
Deficiency of Vitamin D will cause?
- Rickets (in children)
2. Osteomalacia (in adults)
Physical exam findings of Rickets?
Vitamin D deficient child
- Frontal bossing, square head, bowing of legs
Physical exam findings of Osteomalacia?
Vitamin D deficient adult
- Bones tend to fracture easily
Toxicity of Vitamin D will result in?
Hypercalcemia and calcification of soft tissues
Absorbic Acid
Vitamin C
Deficiency of Vitamin C will cause?
Impaired collagen formation
= IMPAIRED HEALING and frequent hemorrhages!!
Where does Vitamin C come from?
ONLY DIET
Secondary Vitamin C deficiency?
Erratic diet and eating patterns in older adults that live alone
Scurvy is deficient in what vitamin?
Vitamin C deficiency
Iron deficient
Hypochromic Microcytic Anemia
BMI levels
Normal - 18.5 - 25
Overweight - 25 - 30
Obese - > 30
Anabolic circuits effect?
Increase food intake
What hormone increases food intake?
Ghrelin
Catabolic circuit effect?
Increased energy expenditure
What 2 things can adipose tissues release to inhibit food intake and promote fat burn?
Leptin
Adiponectin
Obesity can cause insulin resistance. What metabolite will be increased that can contribute to cancers?
IGF-1
High levels of IGF-1 are due to?
Increased insulin levels due to insulin resistance of obesity