Gram (-) Bacteria - Respiratory and Zoonotic Bacilli Flashcards
What are 3 respiratory pathogens?
Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae
What are 3 respiratory pathogens?
Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae
What toxin is involved with Bordetella Pertussis?
Pertussis Toxin
What does the Pertussis Toxin increase and decrease?
Increases CAMP and Histamine
Decreases phagocytosis
Cascade of symptoms with Bordetella Pertussis?
Cold - sneezing, rhinorrhea, fever
1-2 weeks later
Whooping cough
Can then progress to pneumonia
Describe a whooping cough and what is it seen with?
Hacking cough followed by a high pitched inspiratory whoop
– Seen with Bordetella Pertussis
Where is Legionella Pneumophila found?
Water systems
What 2 diseases are a consequence of Legionella Pneumophila?
Pontiac Fever
Legionnaire’s Disease
Pontiac Fever
- Consequence of Legionella Pneumophila
= Self - limited Febrile illness - 2-5 days
Legionnaire’s Disease
- More severe consequence of Legionella Pneumophila
= Multilobar pneumonia with abscess
Haemophilus Influenzae - encapsulated or nonencaspsulated version is more dangerous?
Encapsulated - due to capsule protecting from phagocytosis
What does Haemophilus Influenzae require for growth in the blood?
Hemin and NAD (X and V factors)
What vaccination is important in infant life for Haemophilus Influenzae?
Hib
Symptoms of infection with encapsulated Haemophilus Influenzae?
Early childhood meningitis Acute epiglottitis (drooling, sore throat, wheezing)
Symptoms of infection with nonencapsulated Haemophilus Influenzae?
Otitis Media