Gram (-) Bacteria - Respiratory and Zoonotic Bacilli Flashcards

1
Q

What are 3 respiratory pathogens?

A

Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae

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2
Q

What are 3 respiratory pathogens?

A

Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae

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3
Q

What toxin is involved with Bordetella Pertussis?

A

Pertussis Toxin

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4
Q

What does the Pertussis Toxin increase and decrease?

A

Increases CAMP and Histamine

Decreases phagocytosis

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5
Q

Cascade of symptoms with Bordetella Pertussis?

A

Cold - sneezing, rhinorrhea, fever
1-2 weeks later
Whooping cough
Can then progress to pneumonia

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6
Q

Describe a whooping cough and what is it seen with?

A

Hacking cough followed by a high pitched inspiratory whoop

– Seen with Bordetella Pertussis

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7
Q

Where is Legionella Pneumophila found?

A

Water systems

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8
Q

What 2 diseases are a consequence of Legionella Pneumophila?

A

Pontiac Fever

Legionnaire’s Disease

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9
Q

Pontiac Fever

A
  • Consequence of Legionella Pneumophila

= Self - limited Febrile illness - 2-5 days

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10
Q

Legionnaire’s Disease

A
  • More severe consequence of Legionella Pneumophila

= Multilobar pneumonia with abscess

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11
Q

Haemophilus Influenzae - encapsulated or nonencaspsulated version is more dangerous?

A

Encapsulated - due to capsule protecting from phagocytosis

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12
Q

What does Haemophilus Influenzae require for growth in the blood?

A

Hemin and NAD (X and V factors)

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13
Q

What vaccination is important in infant life for Haemophilus Influenzae?

A

Hib

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14
Q

Symptoms of infection with encapsulated Haemophilus Influenzae?

A
Early childhood meningitis
Acute epiglottitis (drooling, sore throat, wheezing)
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15
Q

Symptoms of infection with nonencapsulated Haemophilus Influenzae?

A

Otitis Media

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16
Q

Other Gram (-) bacteria associated with genital presentations?

A

Chancroid

Gardnerella Vaginalis

17
Q

What factors are required for growth of Chancroid (Haemophilus Ducreyi)?

A

Hemin and NAD (X and V factors)

18
Q

Chancroid - Haemophilus Ducreyi is a _____ disease

A

Sexually transmitted disease

19
Q

What are the 2 symptoms of infection with Chancroid - Haemophilus Ducreyi?

A

PAINFUL genital ulcer

PAINFUL pus forming lymphadenopathy

20
Q

What other sexually transmitted disease has painful genital ulcers but NO pus forming lymphadenopathy to separate it from Chancroid?

A

Herpes

21
Q

What causes Bacterial Vaginitis?

A

Gardnerella Vaginalis

22
Q

What type of cells are detected on pap smear to indicate Gardnerella Vaginalis?

A

Clue cells

23
Q

Symptoms of infection with Gardnerella Vaginalis?

A

Fishy smelling discharge

Pruritus and Dysuria

24
Q

List 5 Zoonotic Bacilli

A
Yersinia Pestis
Francisella Tularensis
Brucella Species
Pasturella Multocida
Bartonella Species
25
Q

What shape is Yersinia Pestis?

A

Safety pin - bipolar shape

26
Q

Describe how people become infected with Yersinia Pestis

A

Prairie dogs and wild rodents –> Fleas –> People

27
Q

What plagues are associated with Yersinia Pestis?

A

Bubonic Plague

Pneumonic Plague

28
Q

Symptoms of Bubonic Plague

A
  • Yersinia Pestis

= Hemorrhage under skin, hot painful lymph nodes, fever

29
Q

Pneumonic Plague is what ____ is spread to ____ from ____

A

Bubonic Plague is spread to humans from humans

30
Q

In what animals is Francisella Tularensis found?

A

Rabbits, tick or deerflies

31
Q

Symptoms of infection with Francisella Tularensis?

A

Similar to Bubonic plague - hemorrhage under skin, hot painful lymph nodes and SKIN ULCER

32
Q

In what animal produces is Brucella Species found?

A

Domesticated animal products - unpasteurized milk, meat, placenta
– cows, goats, pigs

33
Q

Unique symptoms of infection with Brucella Species?

A

Undulating fever - high during day and low during night
Night sweats
Joint pain
Anemia and Leukopenia

34
Q

How is one infected with Pasturella Multocida?

A

Cat scratch or bite, maybe dog

35
Q

Symptoms of infection with Pasturella Multocida?

A

Localized wound infection - cellulitis

36
Q

Cat scratch disease bacteria?

A

Bartonella Species

37
Q

Bartonella Species causes?

A

Cat scratch disease

38
Q

Symptoms of Bartonella Species infection?

A

Fever, malaise, lymphadenopathy
Red nodules
Angiomatosis

39
Q

Angiomatosis

A
  • Seen with Bartonella Species infection

= Vascular proliferation