Gram (-) Bacteria - Respiratory and Zoonotic Bacilli Flashcards
What are 3 respiratory pathogens?
Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae
What are 3 respiratory pathogens?
Bordetella Pertussis
Legionella Pneumophila
Haemophilus Influenzae
What toxin is involved with Bordetella Pertussis?
Pertussis Toxin
What does the Pertussis Toxin increase and decrease?
Increases CAMP and Histamine
Decreases phagocytosis
Cascade of symptoms with Bordetella Pertussis?
Cold - sneezing, rhinorrhea, fever
1-2 weeks later
Whooping cough
Can then progress to pneumonia
Describe a whooping cough and what is it seen with?
Hacking cough followed by a high pitched inspiratory whoop
– Seen with Bordetella Pertussis
Where is Legionella Pneumophila found?
Water systems
What 2 diseases are a consequence of Legionella Pneumophila?
Pontiac Fever
Legionnaire’s Disease
Pontiac Fever
- Consequence of Legionella Pneumophila
= Self - limited Febrile illness - 2-5 days
Legionnaire’s Disease
- More severe consequence of Legionella Pneumophila
= Multilobar pneumonia with abscess
Haemophilus Influenzae - encapsulated or nonencaspsulated version is more dangerous?
Encapsulated - due to capsule protecting from phagocytosis
What does Haemophilus Influenzae require for growth in the blood?
Hemin and NAD (X and V factors)
What vaccination is important in infant life for Haemophilus Influenzae?
Hib
Symptoms of infection with encapsulated Haemophilus Influenzae?
Early childhood meningitis Acute epiglottitis (drooling, sore throat, wheezing)
Symptoms of infection with nonencapsulated Haemophilus Influenzae?
Otitis Media
Other Gram (-) bacteria associated with genital presentations?
Chancroid
Gardnerella Vaginalis
What factors are required for growth of Chancroid (Haemophilus Ducreyi)?
Hemin and NAD (X and V factors)
Chancroid - Haemophilus Ducreyi is a _____ disease
Sexually transmitted disease
What are the 2 symptoms of infection with Chancroid - Haemophilus Ducreyi?
PAINFUL genital ulcer
PAINFUL pus forming lymphadenopathy
What other sexually transmitted disease has painful genital ulcers but NO pus forming lymphadenopathy to separate it from Chancroid?
Herpes
What causes Bacterial Vaginitis?
Gardnerella Vaginalis
What type of cells are detected on pap smear to indicate Gardnerella Vaginalis?
Clue cells
Symptoms of infection with Gardnerella Vaginalis?
Fishy smelling discharge
Pruritus and Dysuria
List 5 Zoonotic Bacilli
Yersinia Pestis Francisella Tularensis Brucella Species Pasturella Multocida Bartonella Species
What shape is Yersinia Pestis?
Safety pin - bipolar shape
Describe how people become infected with Yersinia Pestis
Prairie dogs and wild rodents –> Fleas –> People
What plagues are associated with Yersinia Pestis?
Bubonic Plague
Pneumonic Plague
Symptoms of Bubonic Plague
- Yersinia Pestis
= Hemorrhage under skin, hot painful lymph nodes, fever
Pneumonic Plague is what ____ is spread to ____ from ____
Bubonic Plague is spread to humans from humans
In what animals is Francisella Tularensis found?
Rabbits, tick or deerflies
Symptoms of infection with Francisella Tularensis?
Similar to Bubonic plague - hemorrhage under skin, hot painful lymph nodes and SKIN ULCER
In what animal produces is Brucella Species found?
Domesticated animal products - unpasteurized milk, meat, placenta
– cows, goats, pigs
Unique symptoms of infection with Brucella Species?
Undulating fever - high during day and low during night
Night sweats
Joint pain
Anemia and Leukopenia
How is one infected with Pasturella Multocida?
Cat scratch or bite, maybe dog
Symptoms of infection with Pasturella Multocida?
Localized wound infection - cellulitis
Cat scratch disease bacteria?
Bartonella Species
Bartonella Species causes?
Cat scratch disease
Symptoms of Bartonella Species infection?
Fever, malaise, lymphadenopathy
Red nodules
Angiomatosis
Angiomatosis
- Seen with Bartonella Species infection
= Vascular proliferation
