Oral tumours, oral surgery & stick injuries Flashcards
Give an overview of oral tumours?
- Tumours can arise from bone, teeth or soft tissue structures of the lower (mandible) or upper (maxilla) jaw, or the tongue or pharynx
- Cat most common SCC
- Most tumours of the oral cavity are malignant
- Malignant melanoma and squamous cell carcinoma most common in dogs
- Squamous cell carcinoma most common in cats
- Other malignant tumours include:
- Fibrosarcoma
- Osteosarcoma
- Multilobular osteochondrosarcoma
Discuss tumour diagnosis?
You can’t just look at a tumour and decide what it is need to send off for histopath
Look at some of these examples of tumours?
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Look at some of these examples of tumours?
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Look at some of these examples of tumours?
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Look at some of these examples of tumours?
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Benign tumours are also common and include (naming of benign tumours varies):
- Acanthomatous ameloblastoma (aka basal cell tumour by old vets)
- Peripheral odontogenic fibroma (aka epulis, fibrosing epulis)
Surgery is the mainstay treatment for the majority of malignant and benign tumours
Other treatments options (instead or in addition to surgery) include:
- Radiation therapy
- Chemotherapy
- Immunotherapy (there is a melanoma vaccine available but need to be qualified oncologist to order from USA and not all melanomas respond to the vaccine)
Oral tumours overview?
- Oral tumours are relative common in cats and dogs
- Benign and malignant tumours of the oral cavity account for 3-12% of all tumours in cats and 6% of all tumours in dogs
Oral tumour clinical signs?
- Presence of a mass in the oral cavity
- Increased salivation, blood in the saliva, odorous breath
- If involving alveolar bone teeth may be loose
- Swelling on the face or bulging of the eye (exophthalmos)
- Bloody nasal discharge
- Difficulty eating or pain on opening the mouth, weight loss and enlarged lymph nodes in the neck region
- Loose teeth, especially in animals with general good teeth, may be indicative of cancer-induced bone loss, especially in cats
How to diagnose oral tumours?
Physical examination
- Concomitant problems
- Size and site of oral mass
- Evaluation of regional lymph nodes
Blood tests
FNA
- Often non-diagnostic as requires the lesion to exfoliate (apart from SCC which may exfoliate)
Core biopsy
- Histopathology (bony lesions might prove difficult to obtain representative sample)
Imaging of the skull
- Conventional radiography
- Ideally, CT scan
- To assess bone involvement and degree of margins and aggressiveness
Staging
- Fibrosarcoma(local), osteosarcoma and SCC (will spread to peripheral sites e.glung)
- Conventional radiography
- Ideally, CT scan Oral tumours-diagnostics
Oral tumour treatment options?
Treatment options depend on the location of the tumour and on the type (biology) of the tumour
- benign tumours excised with 1 cm margins
- Malignant tumours excised with 2-3 cm margins
Mandibulectomy
- Unilateral rostral
- Bilateral rostral
- Segmental
- Caudal
- hemimandibuletomy
Maxillectomy
Immunotherapy for melanoma in dogs
Outline mandibulectomy surgery?
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Discuss Epulis-peripheral odontogenic fibromas?
- Derived from cells of the periodontal ligament
- There is bone involvement. If you radiographed likely to see lysis around teeth root
- Benign tumour type
- Aim in removal get margin that includes local bone and teeth it is associated with
- Typically, dogs over the age of six (but can be seen at any age); rare in cats
- Common tumour type that is often misnamed as epulis when it should be called peripheral odontogenic fibromas
- Has a relatively good outcome post surgery
- Curative surgery requires taking away bone and teeth local to tumour
What can be seen here?
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What can be seen here?
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What can be seen here?
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What can be seen here?
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What can be seen here?
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What can be seen here?
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