Lec 6 Antigen Recognition, Processing, Presentation

Question 1

three antigen presenting cells

Answer 1

monocytes/macrophages, b cells, dendritic cells

Question 2

dendritic cells present the antigen via blank

Answer 2

pinocytosis

Question 3

cells that recognize antigen specifically

Answer 3

t cells, b cells

Question 4

8-10 aa are recognized by blank

Answer 4

class 1

Question 5

14-20 aa are recognized by blank

Answer 5

class 2

Question 6

two types of t cells

Answer 6

cd4, cd8

Question 7

cd4 t cells are blank t cells and recognize antigens in association with blank mhc molecules

Answer 7

helper, class 2

Question 8

cd8 t cells are blank t cells and kill cells that present antigens. is a receptor for blank mhc molecules

Answer 8

cytotoxic, class 1

Question 9

all cells of body present antigen to blank t cells

Answer 9

cd8

Question 10

molecules which recognize a variety of structurally conserved molecules of microbes

Answer 10

TLRs

Question 11

strong immunogens bind blank to mhc than weak immunogens

Answer 11

better

Question 12

in the blank, class 1 and class 2 blank

Answer 12

segregate

Question 13

class 1 goes directly to the blank after segregation

Answer 13

cell surface

Question 14

class 2 goes to the blank after segregation

Answer 14

lysosomal like compartment

Question 15

activation of a cd8 cell requires a blank secondary signal than those required for the activation of a cd4 cell

Answer 15

stronger

Question 16

produced by pathogens ranging from bacteria to mammalian retroviruses

Answer 16

superantigens

Question 17

superantigens bind to both mhc class blank molecules as well as tcr alpha beta simultaneously

Answer 17

2

Question 18

superantigens stimulate most t cells that express a given blank sequence

Answer 18

alpha, beta

Question 19

R: antigen recognition by blank cells is restricted by the blank so you cant take t cells from another person and expect them to work

Answer 19

t, mhc

Question 20

R: know class 1 and class 2 inside and out

Answer 20

ok