Lec 3 - Antigens Flashcards
A compound able to combine with elements of acquired immunity
Antigen
Proteins, polysaccharides, particulate antigens are blank immunogens
Strong
Lipids, steroids, nucleic acids are blank immunogens
Weak
Minimal components that are used by the immune system to recognize a particular antigen
Antigenic determinants (epitopes)
A b cell producing antibodies can only produce antibodies that are effective against one type of blank
Epitope
Larger immunogen means more blank
Complex
More complex an antigen, the blank the response
Better
Substances that are added to an immunogenic entity can make it more immunogenic
Adjuvant
Adjuvant cannot make something that is not originally blank, immunogenic
Immunogenic
Thymic independent antigens have responses limited to blank and have poor immunological blank
IgM, memory
Haptens can be made immunogenic when attached to something blank
Immunogenic
Haptens can or cant be made immunogenic by adjuvants
Cannot
Reaction of an antibody with an antigen other than the one that induced its formation
Immunological cross reaction (IMPORTANT)
Antigen antibody bonds are not blank
Covalent
Forces that can hold antigen antibody complex together
Van der waals, hydrophobic, hydrogen bonds, electrostatic forces
Antibody blank binds with the antigen blank
Paratope, epitope
Antibody raised against a particular antigen may blank with another antigen if the second antigen contains antigenic determinants found in the first
Cross react
Antibody may only recognize an antigen if it is in the proper blank
Conformation (primary, secondary, tertiary)
Compound capable of inducing an immune response
Immunogen
