Lec 5-4 - Respiratory Pathogens Flashcards
lower respiratory tract used to be considered blank but isnt anymore
sterile
most common cause of otitis media
nontypeable haemophilus influenzae then strep pneumoniae then moraxella catarrhalis
old questions for this section
ok
population most affected by otitis media
kids and immunocompromised
haemophilus influenze is a blank coccobacillus or pleomorphic rods
gram negative anaerobic
h influenzae lives in the blank resp tract
upper
h influenzei is blank hemolytic
not
h influenze is motile or not
not
h influenzae requires these factors for in vitro growth
x (hemin), v (nad)
Hib only occurs in humans and is the main cause of blank and is the main disease causing strain
meningitis
nontypeable H influenzae is blank which is very important
unencapsulated
nontypeable H influenzae can be in the lower respiratory tract of people with blank
copd
nontypeable cant get into the blood because it doesnt have a capsule but blank can
hib
nthi has a blank which causes a severe inflammatory response
LPS lipid A
chronic otitis media is associated with blank
biofilms
there is a vaccine for blank but not for blank
hib, nthi
causes pertussis (whooping cough)
bordetella
bordetella is gram blank coccobacilli and is strictly blank
negative, aerobic
bordetella cannot survive here and is blank growing
outside body, slow
two stages of pertussis
paroxysmal, convalescent
stage characterizied by crazy bouts of coughing with an inspiratory whoop and can lead to seizures
paroxysmal
convalescent stage is characterized by
declining number of lymphocytes
first two weeks after cough onset, best diagnostic test
culture/pcr
after four weeks, best test is blank
serology
• Know the difference between Type b and Non Typeable
• How to treat/prevent the Non typeable and disease of those two organisms
• Bordetella
o Focus on stages
o Characteristics
o Clinical symptoms
o Virulence factors
o How to treat and prevent
• There will be no questions on Moraxella
ok
