Lec 1-5 - Virology

Question 1

animal viruses are between blank and blank in diameter

Answer 1

25-300 nm

Question 2

classic EM technique to look at viruses

Answer 2

negative staining

Question 3

new EM technique to look at viruses

Answer 3

cryoEM

Question 4

viral genome can be blank or blank but not both

Answer 4

dna, rna

Question 5

viral genome is blank stranded

Answer 5

single or double

Question 6

positive polarity viral genome means blank but a virus can be negative polar as well

Answer 6

message sense

Question 7

these viruses are infectious on their own

Answer 7

dna, positive stranded rna

Question 8

all rna viruses except those with sing strand positive polarity genome requires a blank to become infectious

Answer 8

virion

Question 9

where the genome is in a virus

Answer 9

core

Question 10

protein shell encasing viral genome

Answer 10

capsid

Question 11

capsid with genome of virus

Answer 11

nucleocapsid

Question 12

lipid bilayer with viral proteins inserted

Answer 12

envelope

Question 13

viral glycoproteins in the envelope called spike

Answer 13

peplomer

Question 14

infections viral particle

Answer 14

virion

Question 15

every virus has a blank that surrounds the blank and is usually icosahedral or helical

Answer 15

capsid, genome

Question 16

if a virus has a blank, it is derived from a blank

Answer 16

envelope, host cell membrane

Question 17

classification of viruses based on structure

Answer 17

family, sub family, genus, species

Question 18

dna viruses are all blank excepto for parvoviruses

Answer 18

double stranded

Question 19

there are no blank shape animal viruses

Answer 19

naked helical

Question 20

all viruses are blank

Answer 20

haploid

Question 21

all retroviruses are blank

Answer 21

diploid

Question 22

steps of virus growth cycle

Answer 22

attachment, penetration, uncoating, replication, assembly, maturation/release

Question 23

viruses are known as blank parasites because they need the cell to replicate

Answer 23

obligate intracellular parasites

Question 24

viruses are replicated by blank… not by binary fission

Answer 24

assembly line kind of

Question 25

dna codes for rna primed rna polymerase to create a negative strand in blank replication

Answer 25

positive ss rna replication

Question 26

rna primed rna polymerase makes complement positive strand which can go into the genome or function as a message to make more protein… must be converted to positive

Answer 26

negative ss rna replication

Question 27

replication where ds intermediate integrates into cell dna

Answer 27

retrovirus replication

Question 28

this replication also requires a virion rna polymerase

Answer 28

ds rna polymerase

Question 29

first step of this replication is to convert it to dsDNA

Answer 29

ss DNA