*Lec 1-2 Immunoprophylaxis & Immunotherapy NEW

Question 1

2 eradicated diseases thanks to vaccines

Answer 1

polio, smallpox

Question 2

most common routes of vaccination

Answer 2

intramuscular, subcutaneous

Question 3

two toxin mediated diseases

Answer 3

tetanus, diptheria

Question 4

immunizing with toxin is dangerous so a blank is made and a blank is required

Answer 4

toxoid, adjuvant

Question 5

substance that facilitates or enhances IR to a coadministered vaccine antigen

Answer 5

adjuvant

Question 6

two types of adjuvants

Answer 6

physical, molecular

Question 7

physical adjuvant has a blank release of antigen and induce blank

Answer 7

sustained, inflammasomes

Question 8

molecular adjuvants induce blank but are often blank products

Answer 8

inflammasomes, bacterial

Question 9

extracellular bacterial infections are highly blank

Answer 9

reactogenic (cause swelling at injection site)

Question 10

extracellular bacterial infections are immunized with blank

Answer 10

killed bacteria

Question 11

intracellular bacterial infections are immunized with blank

Answer 11

live bacteria

Question 12

molecular adjuvants most importantly enhance blank molecules on the APC

Answer 12

co stimulatory 2nd signal

Question 13

viral infections are immunized with blank

Answer 13

inactivated virus, (some can be live attenuated viruses)

Question 14

these are needed to induce extracellular bacterial infection vaccines

Answer 14

bactericidal antibody + complement, opsonizing antibody

Question 15

these are needed to induce intracellular bacterial infection vaccines and viral

Answer 15

cell mediated immunity

Question 16

these are needed to induce viral infection vaccines

Answer 16

neutralizing antibody, cytotoxic t lymphocytes

Question 17

this is a use of vaccine involving repeated immunization with small doses of allergen

Answer 17

allergen desensitization

Question 18

allergic desensitization replaces blank with other less harmful Ab isotypes

Answer 18

IgE

Question 19

these vaccines enhance immunity against existing disease

Answer 19

therapeutic vaccines

Question 20

administration of an agent to induce or modify an immune response or inflammatory process especially to treat an existing disease or condition

Answer 20

immunotherapy

Question 21

immunization that involves preformed antibodies like those passed from mother to fetus

Answer 21

passive immunization

Question 22

immunization that involves vaccines

Answer 22

active immunization