Lec 10 Cell Mediated Immunity

Question 1

t cell independent cell mediated responses

Answer 1

chemotaxis, phagocytosis, release of cytokines

Question 2

directed movement of leukocytes along concentration gradient

Answer 2

chemotaxis

Question 3

chemotaxis chemoattractant complement fragment

Answer 3

c5a

Question 4

tnf alpha is a cytokine that comes from macrophages and destroys blank

Answer 4

tumor

Question 5

this cytokine comes from nk cells

Answer 5

interferon gamma

Question 6

Th1 key cytokine

Answer 6

gamma interferon

Question 7

Th2 key cytokine

Answer 7

IL4

Question 8

common denominator for antibody dependent cell mediated cytotoxicity

Answer 8

Fc (CD16) receptor for IgG

Question 9

macrophages are a jack of all trades and can do all of these

Answer 9

non specific response, antigen presentation, effector cells

Question 10

macrophages have a blank activation scheme because macrophages can have so many different blank

Answer 10

complex, effectors

Question 11

cell mediated immunity in which the primary defense mechanism against intracellular bacteria is a macrophage

Answer 11

delayed type hypersensitivity (DHT)

Question 12

three phases of delayed type hypersensitivity

Answer 12

cognitive (antigen recognition), activation (t cells secrete cytokines and proliferate), effector (divided into two steps

Question 13

persistent antigen presence with continual release of cytokines and accumulation of t cells and macrophage like multinucleated cells

Answer 13

granulomas

Question 14

excessive release of blank can lead to shock and hemorrhage

Answer 14

tnf alpha