Lec 12 - Cell Migration/Phagocytosis Flashcards

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1
Q

all leukocytes can do this which is preferential migration of cells so they “know” how to get back

A

homing

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2
Q

first line of defense

A

neutrophils

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3
Q

a biochemical event that causes an increase in oxidative metabolism of phagocytes following uptake of opsonized particles

A

respiratory burst

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4
Q

t cell migration crosses cells by blank

A

diapedesis

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5
Q

unlike lymphocytes, neutrophils make a blank journey from bone marrow to tissue

A

one way

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6
Q

main contributor to inflammation

A

neutrophil

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7
Q

main contributor to chronic autoimmune reactions

A

cd4 T cells

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8
Q

main contributor to asthma

A

eosinophils, basophils, macrophages

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9
Q

toll like receptors can recognize these

A

LPS, bacterial flagellin, viral ss/ds RNA, bacterial dna

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10
Q

two types of adhesion molecules

A

integrins, selectins

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11
Q

homing receptor in lymphocyte circulation

A

L selectin

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12
Q

mediates adhesion of memory t cells and nk cells and neutrophils in response to inflammation

A

e selectin

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13
Q

this is involved in blood clotting

A

p selectin

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14
Q

all beta integrins share this

A

cd18

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15
Q

defect in cd18 causes this

A

leukocyte adherence deficiency

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16
Q

leukocyte adherence deficiency is life threatening due to blank

A

recurrent infections

17
Q

these modulate adhesins

A

cytokines