Lec 2-4 - Parasitology Flashcards
2 parasites in the oral cavity
entamoeba gingivalis, trichomonas tenax
oral amoebiasis is an infection of the oral cavity with blank… causes periodontitis and gingivitis
E. gingivalis
E. gingivalis is not seriously pathogenic but can maintain a stage of blank and allow the growth of blank
chronic irritation, other pathogens
tiny flagellate that is a commensal but can take part in the first phases of periodontal tissue destruction
trichomonas tenax
virulence factor of trichomonas tenax
acid phosphatase
cause of malaria
plasmodium
most deadly malaria species
plasmodium falciparum
transmission of malaria is via
anopheles (female mosquitos)
flu like symptoms from malaria run in blank that are timed with bursting open of rbc which releases debris
cycles
malaria that doesnt show periods of cycles
falciparum
falciparum is the most severe malaria because it can infect blank
red blood cells of all ages
falciparum goes through blank of infected rbc via cytoadherence and rosetting
sequestration
attachment to receptors on venular and capillary endothelia
cytoadherence
clumping of infected rbc with uninfected rbcs which leads to anoxia
rosetting
variant surface antigens of falciparum
PfEMP1 proteins
PfEMP1 proteins are present in knob structures on parasitized blank surface
rbc
falciparum does not cause malaria blank
relapses
malaria types that cause relapses
p. vivax, p. ovale
these are found in many people throughout the world and are transmitted via fecal-oral, contaminated meat, trans placental
toxoplasma gondii
sexual reproduction of toxoplasma happens only in blank
cats
life cycle of toxoplasmas
tachyzoites, zoitocysts, bradyzoites
toxoplasma are not a really big deal unless you are blank
immunocompromised or pregnant
prevention of toxoplasma by
stay away from cats and litter, wash hands after soil contact like gardening
toxoplasma secretes kinases and phosphatases into host cell and messes with blank
transcription
most virulent toxoplasma
type 1
toxoplasma blank kinase from type 1 that is active and activates blank which is a host transcription factor
rop16, stat6
toxoplasma can be treated similarly to malaria but must be taken blank
for life