Lec 3-5 - Viral Hepatitis Flashcards
hep a caused by blank
picornaviridae
hep b caused by blank
hepadnaviridae
hep c caused by blank
flaviviridae
hep d caused by
not sure
most hep has blank genomes
ssRNA
only hep virus with dsDNA genome
B
only hep viruses that arent sexual and are fecal oral instead
A, E
most deadly hepatitis
B then C
most chronic hepatitis
C then B
hep blank infects like 15 million people but only causes problems in those who already have hep B
D
this hep is an acute infection that replicates in intestinal cells
A
two phases of hep A infection
pre ecteric, icteric
icteric means blank
jaundice
fever, lack of energy, anorexia, vomiting phase
pre icteric
icteric phase has blank inflammation and necrosis, dark urine, blank is excreted into blood, most patients recover after 1-2 weeks
liver, bilirubin
this appears 1-2 months after infection and lasts for a lifetime so wont be infected again
igG
this appears at the same time as IgG but is short lived and can be used for diagnosis of recent infection
igM
there is a blank for hep A
vaccine
infectious hep B particle
dane particle
3 forms of surface antigens of hep B
filamentous particles, spherical particles, dane particles
onset of hep B is blank compared to A
slow
most people blank from hep B
recover
two types of hep B
fulminant, chronic
fulminant is if hep D is developed with hep B…. blank is very high
mortality
hep b vaccine involves blank cells and needs blank doses for being max effective
yeast, 3
advantage of blank vaccine is that you cant get sick from it
sick
drugs for chronic hep B
alpha interferon, lamivudine, baraclude
drugs for chronic hep c
alpha interferon, pegylated alpha interferon, ribavirin + alpha interferon (best treatment)
there is no fda approved blank for hep c
vaccine
new antivirals for hep c virus are very effective but blank
very expensive
hep D is diagnosed by presence of blank
igM antibodies
hep e causes blank infection like hep A
acute
