Human disease L29: dobson upper gi Flashcards

1
Q

Gastrointestinal Disorders are common, and defined by their anatomical locations, where are these 4 locations

A

upper gi

lower gi

pancreas

biliary system - livver, gallbladder and associated ducts

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2
Q

the small intestine is broken down in to three parts , name the parts

A

duodenum

jejunum

ileum

(DJ ileum)

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3
Q

the guts fuction is digestion and absorption

what two things can the stomach absorb

A

alcohol and weak acids (aspirin)

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4
Q

the small intestine absorbs products of digestion such as carbohydrates, protein, electrolytes, vitamins, and water.

where is iron primarily absorbed in the small intestine

A

duodenum

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5
Q

the small intestine absorbs products of digestion such as carbohydrates, protein, electrolytes, vitamins, and water.

where is folate primarily absorbed in the small intestine

A

jejunum

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6
Q

the small intestine absorbs products of digestion such as carbohydrates, protein, electrolytes, vitamins, and water.

where is vitamin B12 primarily absorbed in the small intestine

A

ileum

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7
Q

the pancreas is made up of endocrine and exocrine tissues. how are these tissues different

A

exocrine tissues release enzymes such as pancreatic enzymes (pancreatic proteolytic enzymes, pancreatic amylase, pancreatic lipase)

endocrine tissues release hormones such as insulin and glucagon

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8
Q

would you expect to fine endocrine or exocrine tissues at the islets of langerhans

A

The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells,

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9
Q

which organ is responsible for the metabolism of nutrients (carbohydrates, proteins, and lipds) after adsorption from the gastronintestinal tract?

A

the liver

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10
Q

which organ is responsible for the detoxifying and degrading toxins suuch as - body wastes, hormones, drugs, and foreign compounds

A

the liver

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11
Q

This stored form of glucose is made up of many connected glucose molecules and is called?

A

glycogen

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12
Q

which organ is responsible for plasma protein synthesis

A

the liver

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13
Q

which hormone is responsible for the growth and development of megakaryocytes

A

thrombopoietin

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14
Q

what are megakaryocytes

A

Megakaryocytes are cells in the bone marrow responsible for making platelets, which are necessary for blood clotting.

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15
Q

what is the name of this cell

A

megakaryocyte

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16
Q

what is bilirubin

A

Bilirubin is a yellowish substance in your blood. It forms after red blood cells break down, and it travels through your liver, gallbladder, and digestive tract before being excreted.

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17
Q

The condition of having high bilirubin levels is called

A

hyperbilirubinemia

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18
Q

Many babies are also born with high bilirubin, causing a condition called newborn jaundice. This causes yellow-tinted skin and eyes. It happens because,

A

at birth, the liver often isn’t yet fully able to process bilirubin. This is a temporary condition that usually resolves on its own within a few weeks.

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19
Q

Your gallbladder is responsible for making bile,

what is the function of bile

A

bile is a digestive fluid that helps break down fats before they enter your intestines.

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20
Q

when substances like cholesterol or bilirubin harden in your gallbladder, what do you develop

A

gallstones

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21
Q
  • pain in your upper right abdomen or right below your chest
  • back pain between your shoulders or in your right shoulder
  • feeling sick
  • throwing up

which condition do the above symptoms indicate

A

gallstones

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22
Q

Gilbert’s syndrome is a genetic liver condition that causes your liver to not process what properly

A

bilirubin

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23
Q

what is the function of the gall bladdder

A

concentration and storage of bile (fat digestion / absorption)

24
Q

the bile duct open into the?

25
what colour is bile
yellow it gets its colour from bilirubin
26
dysphagia is the term given for difficulty swallowing. if someone is showing symptoms of dysphagia, why is that worrying?
it could be esophageal cancer
27
discomfort related to upper GI tract (heartburn, pain, acidity) is known as what
dyspepsia
28
what is water brash
Water brash is a symptom of gastroesophageal reflux disease (GERD). Sometimes it's also called acid brash. If you have acid reflux, stomach acid gets into your throat. This may make you salivate more. If this acid mixes with the excess saliva during reflux, you're experiencing water brash
29
what is odynophagia and is it a red flag symptom in esophageal cancer
odynophagia refers to pain on swallowing and is a red flag symptom
30
steatorrhoea is the term given for pale bulky stools, what does this indicate?
this indicates that bile secretion didnt occur, which indicate a probelm in the bile duct, gall bladder or liver
31
what is the term given when you vomit blood
haematemesis
32
the production of dark sticky faeces containing partly digested blood, as a result of internal bleeding or the swallowing of blood, is known as what
melaena
33
Melena is the passage of black, tarry stools. what is term used, for the passage of fresh blood per anus, usually in or with stools.
Hematochezia
34
direct visulaisation of the upper gi tract using an endscope is known as what procedure
endoscopy
35
a colonoscopy examines the entire length of the colon; sigmoidscopy examines only what other section of the colon
only the lower third of the colon
36
a faecal calprotectin test is used to detect what
Calprotectin is a stool (faecal) test that is used to detect inflammation in the intestines.
37
qFIT testing uses specific antibodies against human haemoglobin and quantifies the amount of what? in stool
detects occult (blood you can not visulaise) blood
38
if someone had a positive quantitative faecal immunochemical test, they would go on to have which procedure
colonoscopy
39
men and women in scotalnd are invited to under go qFIT test as part of the bowel cancer screening programme. what ages do the participants fall in to and how often would they get screened
bowel cancer screening programme are offered to men and women from the ages of 50-79 every 2 years
40
which bacteria is the most common cause of peptic ulcer disease
helicobacter pylori
41
if a patient is suffering from dyspepsia and peptic ulcers, which bacteria would you be testing for, and what tests would you do?
urea breath test stool helicobacter antigen test serology (helicobacter pylori)
42
how is a urea breath test done
pylori produces an enzyme called urease, which breaks urea down into ammonia and carbon dioxide. During the test, a tablet containing urea is swallowed and the amount of exhaled carbon dioxide is measured. This indicates the presence of H. pylori in the stomach.
43
what is the name of the test that looks for h pylori in your stool
stool helicobacter pylori antigen test
44
the scientific study or diagnostic examination of blood serum, especially with regard to the response of the immune system to pathogens or introduced substances. is known as?
serology
45
what is oesophagitis
Oesophagitis means inflammation of the lining of the oesophagus. Most cases of oesophagatis are due to reflux of stomach acid which irritates the inside lining of the oesophagus. The lining of the oesophagus can cope with a certain amount of acid.
46
what is esophageal varcies
Esophageal varices are enlarged veins in the esophagus. They're often due to obstructed blood flow through the portal vein, which carries blood from the intestine, pancreas and spleen to the liver. Esophageal varices may leak blood and eventually rupture. This can lead to severe bleeding and life-threatening complications, including death. When this happens, it's a medical emergency
47
Sometimes, violent coughing or vomiting can tear the tissue of your lower esophagus and it can start to bleed. The condition is called a
mallory-weiss tear
48
a sore on the lining of your stomach, small intestine or esophagus, is known as a what?
a peptic ulcer
49
which condition occurs when the lining of the stomach becomes inflamed after it's been damaged
gastritis
50
what is GORD
Gastro-oesophageal reflux disease
51
is a condition in which the flat pink lining of the swallowing tube that connects the mouth to the stomach (esophagus) becomes damaged by acid reflux, which causes the lining to thicken and become red. which condition is being described
barrets esophagus
52
is the medical term for a sensation of a lump in the throat where no true lump exists
globus
53
patients with peptic ulcer disease, what medication should we caution with
NSAIDs
54
what is hematinic deficiency
A hematinic is a nutrient required for the formation of blood cells in the process of hematopoiesis. The main hematinics are iron, B12, and folate. Deficiency in hematinics can lead to anaemia
55
name this condition
angular cheilitis
56
name this condition
glossitis
57