Human disease L13: Endocrinology 2 – Thyroid disease Flashcards

1
Q

Q1: what does TSH stand for?

A

Thyroid stimulating hormone

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2
Q

Q2: which of these is a feature of hypothyroidism?

  1. Tremor,
  2. Diarrhoea,
  3. Weight gain,
  4. Anxiety,
  5. Lid lag?
A

Weight gain

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3
Q

Q3: which of these is a feature of hyperthyroidism?

  1. Constipation,
  2. Depression,
  3. Dry skin,
  4. Heat intolerance,

. Bradycardia?

A

Heat intolerance

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4
Q

Q4: of T4 and T3 which is the active form of the hormone?

A

T3

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5
Q

Q5: what is the general purpose of thyroid hormones?

A

Stimulate an increase in the metabolic rate of many tissues

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6
Q

Q6: too little thyroid hormone – makes metabolic rate slow, this is known as?

A

Hypothyroidism

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7
Q

Q7: too much thyroid hormone – makes metabolic rate fast, this is known as?

A

Hyperthyroidism

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8
Q

Q8: what is the mainstay of testing for thyroid investigations?

A

Blood tests, can detect levels of TSH, T3, T4.

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9
Q

Q9: what is the most common cause of hypothyroidism?

A

The most common cause of hypothyroidism is an autoimmune disorder known as hashimoto’s thyroiditis, this occurs when your immune system produces antibodies that attack your own tissues.

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10
Q

Q10: why do people gain weight in hypothyroidism?

A

Because their metabolic rate has decreased.

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11
Q

Q11: why do people have constipation in hypothyroidism?

A

Hypothyroidism pretty much slows everything down and that includes the transit of bolus in the gut, causing it harden and cause constipation.

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12
Q

Q12: which lifelong drug needs to be given for the treatment of hypothyroidism?

A

Thyroxine

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13
Q

Q13: which oral condition Is more common in hypothyroidism?

A

Oral candidiasis

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14
Q

Q14: what is the most commonest cause of hyperthyroidism?

A

An autoimmune disease called graves disease, where your immune system mistakenly attacks your thyroid which causes it to become overactive.

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15
Q

Q15: what causes lid lag?

A

Lid lag is a condition where ethe muscles of the orbit swell and in doing so, push they eyes out abit. This is as a result of hyperthyroidism.

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16
Q

Q16: graves eyes disease is linked to why thyroid disorder?

A

Hyperthyroidism

17
Q

Q17: how do we treat hyperthyroidism?

A

The treatment of hyperthyroidism is to ultimately supress the release of T4 and T3. This is done through the medication of carbimazole, propylthiouracil.

18
Q

Q18: people exhibiting allot of tremors as a result of hyperthyroidism are given what to manage those symptoms initially?

A

B Blockers to reduce symptoms

19
Q

Q19: uncontrolled hyperthyroidism is a contraindication to the use of what (dental aspect)?

A

The use of adrenaline in LA

20
Q

Q20: what are the side affects of carbimazole and propylthiouracil (dental aspect)?

A

Can cause taste disturbance

21
Q
A