Cardiovascular Physiology 34

Question 1

How does increased preload affect the pressure volume curve?

Answer 1

• Stroke volume given by the width is increased
• The isovolumetric portion of the curve is shifted to the right
• Increase in end diastolic volume

Question 2

How is the End systolic pressure volume relationship (ESPVR) affected by increased preload?

Answer 2

There is no change is the ESPVR

Question 3

What is preload?

Answer 3

The volume of the blood that stretches the ventricle at the end of diastole

Question 4

What is unchanged with increased preload?

Answer 4

The end systolic pressure and volume are unchanged

Question 5

How is ESPVR affected by increase contractility?

Answer 5

The slope of the ESPVR increases

Question 6

What changes on the pressure volume curve when there is increased contractility?

Answer 6

• The slope of ESPVR increases

* ESV decreases resulting in increased SV

Question 7

What is afterload?

Answer 7

The pressure that the heart must work against to eject blood into the aorta during systole

Question 8

What changes in the pressure volume curve when there is increased afterload?

Answer 8

• SV decreases
• ESV increases
• Increased period of isovolumetric contraction

Question 9

How is ESPVR affected by an increased afterload?

Answer 9

It remains the same