ANS Lecture 5 Flashcards
What does the influx of sodium caused by the the binding of ACh to a ligand gated receptor cause?
Voltage gated channels to open and allow more sodium to enter
What do Second Messengers do?
It activates an enzyme called protein kinase which can cause the phosphorylation of various proteins
What can Phosphorylation of various proteins by protein kinase do?
Increase or inhibit the activity of a protein
What are the Transmitters or Hormones in the Signal Transduction Pathways?
ACh, Noradrenaline and adrenaline
What are the receptors in the Signal Transduction Pathway?
Muscarinic and Adrenergic
What are G proteins?
Molecules which transduce extracellular signals into an intracellular response
What are the main Enzymes in the Signal Transduction Pathway?
Adenylate cyclase
Phospholipase
What do the Enzymes in the Signal Transduction Pathway do?
Catalyze the production of Second Messengers
What are common second messengers in the Signal Transduction Pathway?
cAMP, IP3, DAG and calcium ions