Blood 6 Flashcards

1
Q

Which WBC precursors fall under the umbrella of Granulocytes?

A
  • Neutrophils
  • Eosinophils
  • Basophils
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2
Q

Which WBC precursor from the blood becomes a Lymphocyte?

A

B-cells

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3
Q

When do Monocytes become Macrophages?

A

After leaving the blood and entering the tissues

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4
Q

What cells do WBC precursors form in the bone marrow?

A
  • Neutrophils
  • Eosinophils
  • Basophils
  • Monocytes
  • B-cells
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5
Q

What cells do WBC precursors form in the Thymus?

A

T-cells

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6
Q

Where do T-cells go after forming in the Thymus?

A

The blood

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7
Q

What cell do T-cells become after they enter the blood?

A

A Lymphocyte

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8
Q

Where are WBC stem cells located?

A

In the bone marrow

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9
Q

Which white blood cells move into the tissues?

A
  • Granulocytes
  • Macrophages
  • Lymphocytes
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10
Q

When do B-cells become Lymphocytes?

A

After moving into the blood from bone marrow

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11
Q

When do T-cells become Lymphocytes?

A

After moving into the tissues from the Thymus gland

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12
Q

When do Neutrophils, Eosinophils, and Basophils become Granulocytes?

A

After moving into the blood from bone marrow

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13
Q

When do Monocytes become Macrophages?

A

When they move into the tissue from the blood

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14
Q

What are WBC precursors under the influence of when they turn into Granulocytes?

A

Various hormone like molecules

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15
Q

How can the Lymphocytes recycle back into the blood?

A

Through the lymphatic system

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16
Q

What are the appropriate roles of the immune system?

A
  • Defense against invaders

* Removal of own old/damages/abnormal cells

17
Q

What are inappropriate roles of the immune system?

A
  • Exaggerated response to harmless substances (allergies)
  • Autoimmune reactions
  • Rejection of transplants
18
Q

What balance must be kept in the prevention of blood loss?

A

The balance between “Pro-hemostatic” or “Pro-coagulant” vs “Anti-hemostatic” or “Anti-coagulant factors”

19
Q

Which factors prevent blood loss?

A

Pro-hemostatic and Pro-coagulant factors

20
Q

Which factors keep the blood fluid?

A

Antihemostatic ot anticoagulant factors`

21
Q

What is Hemostasis?

A

The prevention of blood loss

22
Q

What are the 3 mechanisms of Hemostasis?

A
  1. Vasoconstriction
  2. Primary Hemostasis or Platelet Plug formation (white thrombus)
  3. Secondary Hemostasis or Blood Clotting or Blood Coagulation (red thrombus)
23
Q

What is the first step in Hemostasis?

A

Vasoconstriction of the blood vessel by smooth muscle

24
Q

Why isn’t vasoconstriction enough to stop blood flow?

A

Because the blood vessel is under very high pressure

25
Q

What is the second step in preventing blood loss?

A

Primary Hemostasis or Platelet Plug formation (white thrombus)

26
Q

What occurs in Primary Hemostasis or Platelet Plug Formation or (white thrombus)?

A

Platelets form a plug to plug up the damaged area of a blood vessel

27
Q

Why isn’t Primary Hemostasis or Platelet Plug Formation or (white thrombus) not always effective?

A

Because blood is under high pressure and the platelet plug can be pushed away

28
Q

What is the quickest response to blood loss?

A

Vasoconstriction

29
Q

Where do Platelets cells come from?

A

Stem cells in the bone marrow that form megakaryocytes

30
Q

Describe the appearance of Megakaryocytes

A

Large cells that have a strange looking nucleus with multiple lobes

31
Q

Which hormone like molecule regulates the production of platelets?

A

Thrombopoietin

32
Q

How does Thrombopoietin regulate the production of Platelets?

A

They cause the cytoplasm of megakaryocytes to break up into fragments and become platelets

33
Q

What do Platelets lack?

A

A nucleus

34
Q

What Granules do Platelets contain?

A

Alpha Granules and Dense Regular Granules

35
Q

What allows interaction between different platelets?

A

Various glycoprotein receptors on the surface