virology Flashcards
negative features
- not visible
- not complex
- not treated with antibiotics
characteristics
core
capsid
envelope
core +capsid
nucleocapsid
genome consists of ….. type of …….. acid
1
nucelic
replication phases
infection
replicating
dormant
Na core holds
genome
protein capsid
has protein sub-units
what does the protein capsid do
protection
what does the protein capsid do in terms of attachment
no envelope is present
replication cycle
entry
multiplication
escape
6 stages
Adsorption Penetration Uncoating Synthesis Assembly Release
in adsorption. attach … to host cell
virion
in adsorption specific host cell
receptors
presence of receptors determines
infectivity
specifics of adsorption
polio virus receptors
primates only
HIV receptors
on T-helper white cells
penetration by T4 phage:
- attach to host cell by tail fibres
- contraction of tail sheath
- rigid tail core driven through cell envlope
- viral DNA is now free to enter host cell
retrovirus
-RNA genomes first copied to DNA then host enzyme and trancribe viral DNA
release
host cells and virions are releases
antiviral therapy
vaccination
inject antibodies
anti-resp strategy
anti-release strategy
