cell singalling 2 Flashcards
1
Q
what does the aq/11 subunit allow hormone/neurotransmitter to happen
A
activate PLC
2
Q
Gq proteins (2nd messenger) are a product of what
A
phopsponiostidester breakdown
3
Q
what do Gq proteins stimulate
A
PLC
4
Q
PLC will cleave PIP2 into what
A
IP3 and DAG
5
Q
What does IP3 stimulate release of
A
calcium
6
Q
what does DAG cause to be recruited
A
PKC
7
Q
the release of calcium allows cam and calcium to bind. How many calcium ions bind to cam
A
4
8
Q
what do cam-ca activate
A
PDE and CAM kinases
9
Q
fill in the blanks:
1 adrenoreceptors cause …….. smooth muscle ………. via …..PLC…..
A
vascular
contraction
Gq
IP3
10
Q
fill in the blanks:
2 adrenoreceptors cause ………. smooth muscle….. via …..…. inhibition of ………..
A
vascular
contraction
Gi
CAMP-PKA
11
Q
what recpeptors cause relaxation via Gs-cAMP-Pka
A
b1/b2 adrenoreceptors
