Route Of Admin (capsules) Flashcards
1
Q
Advantages of capsules
A
Easy to swallow
Easy to handle
Mask taste and smell
Minimal excipients
2
Q
Disadvantages of capsules
A
Not suitable for highly soluble substances
3
Q
What are the types of capsules and how many pieces in each
A
Hard -2
Soft -1
4
Q
How do you make gelatine using acid process
A
- acidify to ph 4
- heat from 50 C to boiling
- eliminate fat
- filter
- vacuum evap
- drying
5
Q
How do yo make gelatine alkali process
A
- treat w NAOH
- remove NaOH
- treat with acid to adjust pH
- heat from 50 C to boiling
- demineralise
- filter
- vacuum evaporation
- drying
6
Q
Why is gelatine used
A
- non toxic
- non irritant
- soluble in biological fluids
- produce strong flexible film
7
Q
In hard empty gelatine capsules what should the moisture content be
A
13-16%
8
Q
Different type of filling materials
A
- dry solids
- semisolids
- non-aqueous liquids
9
Q
What are the advantages of soft capsules
A
- better drug absorption
- dose uniformity and precision
- product stability
10
Q
Name the different types of soft gels (5)
A
- oral soft gel
- chewable
- twist-off
- sackable
- meltable
11
Q
What is the composition of soft gels
A
- gelatine
- plasticisers
- water
