Immune system 2 Flashcards
induced innate IR
toll like receptors
NK cells
how many subtypes of toll-like receptors are there
10
what activates TLR in macrophages
LPS
whan a bacterium binds to the receptor and simulates a signal transduction path it will activate
NF-RB
Name the three stages of an interferon response
virus-infected cells
IFN-a IFN B
interferon response
what can the interferon response do
induce resistance to viral replication in all cells
include expression of ligands for receptors on NK cells
activate NK cells to kill virus infected cells
variable region has ……. and ……. and have ……. binding
Vh
Vl
Fab binding
IgG IgD IgA has ………… domain
3 Ch
IgM, IgE, have ……… domain
4
what is the light chain made of
λ & κ
what is heavy chain made of
γ,µ,δ,α,ε
what shape is IgA
dimer
what shape is IgM
pentamer
NK cells:
IFN binds to IFN receptors and activates them
NK cells proliferate and differentiate into
effector NK cells
