Cellular Pathology Flashcards

1
Q

List the 5 adaptive responses

A
Hypertrophy 
Hyperplasia 
Dysplasia 
Metaplasia
Atrophy/hypoplasia
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2
Q

What is hypertrophy

A

Inc the size of organs/cells due to protein accretion

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3
Q

What is hyperplasia

A

Increase in the number of cells and organs

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4
Q

What is dysplasia

A

Change is cell organisation

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5
Q

What is metaplasia

A

Substitute one cell type with another with an organ

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6
Q

What is atrophy/ hypoplasia

A

Decrease cell size and number

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7
Q

What stage are nerve cells in permanent

A

G0

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8
Q

What is prophase

A

Centrioles move to poles

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9
Q

What is metaphase

A

Chromosomes align, nuclei disappears

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10
Q

Anaphase

A

Chromosomes divide and move to poles

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11
Q

What is telophase

A

Nuclear membrane reappears and cytokinesis occurs

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12
Q

2 types of sub-lethal cell injury

A

Hydropic degeneration

Fatty change

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13
Q

Lethal cell injury

A

Necrosis

Programmed cell death

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14
Q

In coagulation necrosis what does the tissue appear as

A

Firm
Pale
Outlined

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15
Q

Causes of coagulative necrosis

A

Ischaemia

Proteins released from dead cells

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16
Q

In liquefactive necrosis how does the tissue appear

A

Semi-solid

Dissolution of the tissues

17
Q

Causes of liquefactive necrosis

A

Infections

Hydrolase release

18
Q

Other 2 necrosis types

A

Enzymatic fat
Caseous
Gangrenous

19
Q

2 pathways of apoptosis

A

Intrinsic

Extrinsic