Solubility Flashcards
What is a solution
Mix of 2 or more components which make a single phase.
Homogenous at molecular level
What is saturation
When the concentration= solubility
What is subsaturation
When concentration is less than solubility
What is supersaturation
When concentration greater than solubility
Stable crystalline
Meta stable crystalline
Amorphous
Does solubility increase or decrease down this list
Increases
Factors which affect solubility
Solute
Environment
Solvent
Solute is affected by
Crystallinity
Ionic nature
Polarity
Dissociation
Environment is affected by
Temperature
Pressure
Solvent is affected by
Ph
Polarity
Ionic composition
When you have solute-solute and solvent-solvent is it endo/exo
Endo
I’d you have solute-solvent what bonds do yo get
Exo
In high ph acidic drug will
Remove h+ by forming H20
Favours ion
If you have a basic drug in low PH what happens
Supplies H+
Favour ionisation
Increase solubility