Source of Drug 1 Flashcards

1
Q

natural products source

A

microorganism

sponges

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2
Q

problems of natural products

A

mixtures are complex and large macro molecules
compound isolation and structure determination is difficult
structure are complex therefore difficult to synthesise

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3
Q

methods of extraction

A

infusion
digestion ‘distillation
decotion

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4
Q

………… is metabolised to ………. ……………. through non-covalent interaction

A

salicin

salicylic acid

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5
Q

aspirin is used to prevent

A

cardiovascular disease

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6
Q

aspirin has ……. effect

A

antipatelet

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7
Q

mechanism of action of aspirin

A

prostaglandin synthase catalyse Aracpidionic acid to PgH2

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8
Q

Thromboxane will

A

stimulate platelet aggregration

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9
Q

cocaine will block

A

dopamine
serotonn
nor epinephrine absorption

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10
Q

caffeine is a

A

stimulant

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11
Q

caffeine is an antagonist of

A

adeposine

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12
Q

What did Paul Ehrlich develop

A

1st antibac drug in modern medicine

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13
Q

antimetabolites are similar to

A

DABA

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14
Q

sulfonamides are a compound inhibitor of

A

DABA

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