Source of Drug 1 Flashcards
natural products source
microorganism
sponges
problems of natural products
mixtures are complex and large macro molecules
compound isolation and structure determination is difficult
structure are complex therefore difficult to synthesise
methods of extraction
infusion
digestion ‘distillation
decotion
………… is metabolised to ………. ……………. through non-covalent interaction
salicin
salicylic acid
aspirin is used to prevent
cardiovascular disease
aspirin has ……. effect
antipatelet
mechanism of action of aspirin
prostaglandin synthase catalyse Aracpidionic acid to PgH2
Thromboxane will
stimulate platelet aggregration
cocaine will block
dopamine
serotonn
nor epinephrine absorption
caffeine is a
stimulant
caffeine is an antagonist of
adeposine
What did Paul Ehrlich develop
1st antibac drug in modern medicine
antimetabolites are similar to
DABA
sulfonamides are a compound inhibitor of
DABA