route of admin (suspension)

Question 1

what is the particle size of a colloidal suspension

Answer 1

<1um

Question 2

what is the particle size of a coarse dispersion

Answer 2

> 1um

Question 3

main disadvantage of suspension

Answer 3

rate of abs is lower than solution

dose uniformity varies except for completely homogenous suspensions

Question 4

in pure water or aqueous solutions what can drug particles do.

Answer 4

undergo self-ionisation to produce ions

Question 5

which layer des a low concentration of excipients affect

Answer 5

diffuse layer

Question 6

which layer des a high concentration of excipients affect

Answer 6

fixed layer

Question 7

below CMC what do the particles cover

Answer 7

they cover the surface

Question 8

above the CMC what do the micelles form with

Answer 8

they form with a hydrophobic core where the drug dissolves

Question 9

DLVO theory explains aggregation of aqueous ……… and forces between ………. surfaces interacting within the liquid

Answer 9

dispersions

charged

Question 10

3 ways that particles move

Answer 10

Brownian
gravity
external agitation