immune system 3

Question 1

immature B cells have ….. affinity for IgM and ….. affinity for IgD

Answer 1

high

low

Question 2

cells enter the ………..

Answer 2

secondary lymphoid tissue

Question 3

B cells are guided by what to congregate in the primary lymphoid tissue

Answer 3

chemokines

Question 4

antigen-specific B cells are activated by

Answer 4

Th cells

Question 5

some activated ………. proliferate in primary follicle and ………..

Answer 5

B cells

differentiate

Question 6

T cell receptor made of

Answer 6

2 polypeptide chain a +B

Question 7

each V chain contributes …..

Answer 7

3CDRS

Question 8

TCR complex has ….. of ……… and E chain

Answer 8

proteins

CD3 complex

Question 9

MHC molecules

Answer 9

2 types

Question 10

MHC molecules have role in ……. rejection

Answer 10

transplant

Question 11

MHC molecules have ———— aa short peptides bind between a1 and a2

Answer 11

8-10

Question 12

MHC molecules are mainly expressed on ……

Answer 12

APC

Question 13

They are made of …. chains and …… extracellular domains

Answer 13

2

2

Question 14

where do negative selection recognise self MHC

Answer 14

on dendritic cells

Question 15

name the 2 selected T cells

Answer 15

CD4

CD8

Question 16

how can cytoxic T cells kills

Answer 16

• apopotosis

- secrete cytotoxic granules