Topical preparations Flashcards

1
Q

adminstered where

A

tissue surface

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2
Q

treat ……. condition

A

local

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3
Q

site of action is site of …………. action

A

therapeutic

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4
Q

to minimise side effect minimise

A

systemic absorption

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5
Q

pros of this route

A

avoid GI degradation
non-invasive
minimise side effect
conveinant

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6
Q

cons of ths route

A

low skin permeability

skin irritation

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7
Q

ointment:

A

drug dissolved

occulusve

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8
Q

creams:

A

semi-solid emulsion
multiphase dispersion
longer residence time than lotion

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9
Q

gel:

A

semi-solid

mostly aqueous

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10
Q

lotion:

A

water based

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11
Q

foam: dispersion of …….. within a ………..

A

gas

liquid

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12
Q

spray: fine mist generated using ………. in ………… can

A

propellant

pressurised

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13
Q

SA of human skin

A

2m2

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14
Q

epidermis has

A

stratueum corneum

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15
Q

corneocytes are what

A

hydophilllic

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16
Q

transcelllar route used for

A

hydrophillic drugs

17
Q

paracellular route

A

lipophillic drugs

18
Q

factors affecting dermal drug transport

A

drug properties:
-lipophillic
-moecular weight
anatomical site