epidemioogy and pathogenicity Flashcards
infectious disease
infection by pathogenic microorganisms
infection
invasion by multiplication of pathogenic microbe within or on a host
infection stages
incubation period
prodromal stage
illness period
decline period
infammation
non spec reaction by cytokines
acute
2.
3.
- asymptomatic
3. chronic
disease time line:
trasmission to host exposure adherance invasion colonisation and growth tissue damage
disease process:
exposure to pathogen adherance to skin invasion through epithelium colonise and grow tissue damage disease
koch’s postulate
specific casuative agent is observed in every disease case
agent isolated from diseased host and grown in pure culture
when agent from pure culture is innoculated into healthy but susceptible hosts agent cause same disease
agent is re-isolated from innoculated diseased host ident
epidemology
study of relationships between various factors that deermine frequency
taxonomy
sys class of living things/organisms
sporatic disease
occasional at regular intervals
endemic
in steady , but low freq @ regular intervals
epidemic
sudden increase in occurrence above expected levels
outbreak
sudden unexpected occurance
index case
1st case in epidemic