Thyroid diseases Flashcards

1
Q

Thyroid disease is very common which gender does it occur in more commonly?

A

-Female

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2
Q

What does excessive activation of the thyroid cause?

A

-Hypermetabolic state that causes protein catabolism and enhanced sympathetic nervous system activity

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3
Q

What are some infrequent ectopic sites in the oral cavity for the thyroid tissue?

A
  • Intra-lingual

- Lingual thyroid

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4
Q

What are the clinical findings of someone with hyperthyroidism?

A
  • Nervousness
  • Hot and sweating
  • Weight loss
  • Muscle weakness/tremor
  • Palpitations/tachycardia
  • Thyroid storm
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5
Q

What are the symptoms of a thyroid storm?

A
  • Fever
  • Tachycardia
  • Sweating
  • Shaking
  • Agitation
  • Unconsciousness
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6
Q

What is the cause of Graves disease?

A

-Autoimmune antibodies function as agonists to thyroid-related receptors causing excessive thyroid receptor activation

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7
Q

T/F Graves disease is responsible for 10% of hyperthyroidism

A

False

-90%

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8
Q

What are the symptoms of Graves disease?

A
  • Hyperthyroidism
  • Exophthalamos (bug eyes)
  • Enlarged thyroid gland
  • Pre-tibial Myxedema
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9
Q

What is Plummer’s disease?

A

-Multinodular goiter and is 5-10% of the hyperthyroidism cases

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10
Q

What is the definition of hypothyroidism?

A

-Hypometabolic state due to decreased thyroid hormone

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11
Q

What type of deficiency can cause hypothyroidism?

A

-Iodine deficiency

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12
Q

If children have hypothyroidism what is that associated with?

A

-Cretinism with reduced mental and physical development

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13
Q

T/F With Hypothyroidism you have an enlarged thyroid

A

True

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14
Q

What are some clinical findings with hypothyroidism?

A
  • Low temperatrue
  • Dry coarse skin and hair
  • Sluggish
  • Cold intolerence
  • Modest weight gain
  • Myxedema
  • High TSH
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15
Q

What causes Hashimoto’s disease?

A
  • Autoimmune T-cell related usually in females

- Hypothyroidism

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16
Q

How does Hasimoto’s disease start?

A

-As hyperthyroidism followed by permanent hypothyroidism

17
Q

What is the most common form of thyroid deficiency in the U.S.?

A

-Hashimoto’s disease

18
Q

What is the most common lesion of the thyroid?

A

-Goiter

19
Q

What is a Goiter usually associated with?

A

-Iodine deficiency

20
Q

How do you diagnose a Goiter?

A

-Fine needle aspiration to determine if they have large follicles filled with colloid and few cells

21
Q

T/F A goiter is a cancer

A

False

-It is not

22
Q

What is the most common thyroid neoplasm?

A

-Thyroid adenoma

23
Q

T/F Thyroid adenomas are malignant

A

False

-They are not

24
Q

What is the most common thyroid carcinoma?

A

-Papillary carcinoma

25
Q

T/F Most thyroid nodules are benign

A

True

26
Q

What do Thiomides do?

A

-Inhibit thyroid peroxidase reaction and block synthesis of hormone

27
Q

What do Iodides-Lugol solution do?

A

-Inhibit hormone release

28
Q

What do beta blockers do in hyperthyroid disease?

A

-Inhibit conversion of T4 to T3

29
Q

What does radiation iodine do in hyperthyroid disease?

A

-Destroys thyroid parenchhyma

30
Q

How do you treat hypothyroidism?

A

-Thyroid replacement such as Synthroid or levothroid

31
Q

What is another name for thiomides?

A

-Propylthiouracil (PTU)