Introduction to the nervous system lecture 2 Flashcards
What classification is a serotonin?
-Indoleamine
What is the precursor to make acetylcholine that enters the nerve?
-Choline
What combines with choline to make acetylcholine?
-Acetyl CoA
What enzyme combines choline with acetyl CoA?
-Choline acetyl transferase
What puts acetylcholine into a vesicle?
-Vesicular Ach transporter
What enzyme metabolizes Ach once it is released back to choline?
-Acetylcholinesterase (this is done very quickly)
Is there an Ach plasma membrane transporter?
-No
Does Ach have an autoreceptor?
-Yes
What can Ach do once it is released?
- Go to an autoreceptor
- Get metabolized back into Choline
- Goes to post synaptic receptors
What are the two types of post synaptic receptors?
- Nicotinic
- Muscarinic
What type of receptor is the autoreceptor?
-Muscarinic
Between GABA and glutamate which one is inhibitory?
-GABA
Between GABA and glutamate which one is excitatory?
-Glutamate
What is the precursor to make glutamate?
-Alpha ketoglutarate
What enzyme changes alpha ketoglutarate to glutamate?
-aminotransferase