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Human disease and therapeutics 2020 > CNS degenerative disorders lecture #3 > Flashcards

CNS degenerative disorders lecture #3 Flashcards

1
Q

What are they ways to manage dental needs in Alzheimer’s disease pts?

A
  • Provide short, simple instructions
  • Use a “watch me” technique
  • Monitor daily oral care
  • Keep up with regular dental visits for as long as possible
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2
Q

What are the clinical manifestations of Multiple Sclerosis?

A
  • Demyleination
  • Site specific
  • Progressive and relapsing/remission
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3
Q

What type of disease is MS?

A

-Demyelination disease leading to inflammation and scarring

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4
Q

T/F The symptoms of MS are site specific

A

True

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5
Q

What can MS effect?

A
  • Senses
  • Autonomics
  • Cognition
  • Depression
  • Fatigue
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6
Q

What does heat and stress do to MS patients?

A

-Stimulate MS episodes

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7
Q

Where do you see most patients with MS?

A

-Places where Scandinavian populations have settled (In the US the northern states)

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8
Q

Is MS genetic?

A

-Yes

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9
Q

Is MS a male or female disease?

A

-More female

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10
Q

When do you start to see MS?

A

-Earlier in life than most other degenerative diseases

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11
Q

How may people in the US have MS?

A

-300,000

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12
Q

What are the initiating factors of MS?

A
  • Possibly a viral infection

- It is an Autoimmune disease

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13
Q

What is the progression of MS like?

A

-It is variable from person to person with relapses/remissions

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14
Q

What are the four classifications of MS?

A
  • Benign
  • Relapsing remission
  • Relapsing progressive
  • Chronic progression
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15
Q

If you have Benign MS what symptoms are associated with it?

A

-Not really any symptoms except maybe some fatigue

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16
Q

If you have relapsing remission of MS what is associated with it?

A

-Symptoms Come and Go (on/off) but there is no worsening of the disease

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17
Q

If you have relapsing progressive of MS what is associated with it?

A

-Symptoms come and go but the severity of the disease continues to progress

18
Q

If you have chronic progression of MS what is associated with it?

A
  • It continually progresses once you start getting symptoms

- Usually fatal

19
Q

Where does MS occur?

A

-In the brain

20
Q

What is the diagnosis and treatment of MS?

A
  • There is no definitive test to diagnose MS

- You can use MRIs to see opacities but that isn’t the only thing that can appear opaque in the brain

21
Q

When do they call is MS?

A
  • If the brain scan has more than 2 areas of opacities

- And if you have the symptoms of MS

22
Q

What do the symptoms of MS depend on?

A

-Where you see the opacities in the MRI

23
Q

How do you manage relapses of MS?

A
  • Prednisone (steroid for anti-inflammation)
  • Interferon (Potent genetic approach to dealing with inflammation)
  • Methyltrexate
24
Q

If you have bowel dysfunction of MS what drug will you give?

A

-Metamucil (psyllium)

25
Q

What symptoms are common with MS?

A
  • Bladder dysfunction
  • Bowel Dysfunction
  • Depression
  • Fatigue
  • Pain
  • Tremors
26
Q

If you have bladder dysfunctions of MS what drug will you give?

A

-Tamsulosin (Flomax)

27
Q

If you have depression with MS what drug will you give?

A

-Prozac

28
Q

If you have fatigue with MS what drug will you give?

A

-Modafinil

29
Q

If you have pain with MS what drug will you give?

A

-Gabapentin (Neurontin) (anti-seizure drug)

30
Q

If you have tremors with MS what drug will you give?

A

-Clonazepam (Klonopin)

31
Q

What does ALS stand for?

A

-Amyotrophic lateral schlerosis

32
Q

What does ALS damage and do?

A

-CNS nerves that destroy voluntary skeletal muscles

33
Q

What is a chronic autoimmune damage to skeletal muscles and diminished contact between neurons and skeletal muscles?

A

Myasthenia gravis

34
Q

What causes Myasthenia Gravis?

A
  • Nueromuscular junction

- Destroy receptors for acetylcholine

35
Q

What drugs do you use for Myasthenia Gravis?

A

-Acetylcholinesterase inhibitor

36
Q

If you stigmine what type of drug is it?

A

-Acetylcholinesterase inhibitor

37
Q

What is a disorder in which the body’s immune system attacks part of the peripheral nervous system?

A

-Guillain-Barrie syndrome

38
Q

When does Guillain-Barre occur?

A

-A few days or weeks after the patient has had symptoms of a respiratory or GI viral infection

39
Q

Extrapyramidal disease includes what groups of clinical disorders?

A
  • Parkinsonism
  • Chorea
  • Athetosis
40
Q

What is an extrapyramidal disease?

A

-It is a functional rather than anatomical unit problem marked by abnormal involuntary movements, alterations in muscle tone and postural disturbances

Human disease and therapeutics 2020 (60 decks)

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