Psychopath lecture 3

Question 1

In stress what happens to the sympathetic activity?

Answer 1

-Increased

Question 2

What are the normal types of anxiety disorders?

Answer 2

-Chronic, mild anxiety

Question 3

What are the symptoms of chronic mild anxiety?

Answer 3

• Tense

- Irritable

Question 4

What is the treatment for chronic mild anxiety?

Answer 4

-Do things that help you relax

Question 5

If you have chronic moderately sever anxiety how long has it been going on for?

Answer 5

-Longer than 6 months

Question 6

What are the symptoms for chronic moderately severe anxiety?

Answer 6

• Poor concentration

- No obvious reason

Question 7

What are the treatment options for chronic moderately sever anxiety?

Answer 7

-Use anxiolytics/sedatives

Question 8

What are the typical drugs used for anxiety?

Answer 8

-Benzodiazepines

Question 9

What do Benzodiazepines act on?

Answer 9

-Agonists for BDZ receptors (decrease activity)

Question 10

What does an agonist on BDZ receptors do?

Answer 10

-It is an allosteric modulator of GABA A receptors

Question 11

What type of effect does Benzodiazepines have respiration?

Answer 11

-Has Little effect

Question 12

What are the most popular CNS depressants?

Answer 12

-Benzodiazepines

Question 13

What are the therapeutic action of Benzodiazepines?

Answer 13

• Anxiolytics
• Treat seizures
• Alcohol withdrawal
• Insomnia (hypnotic short acting)
• Muscle relaxation
• Often used a couple hours before surgical dental procedures

Question 14

What are the adverse effects of Benzodiazepines?

Answer 14

• Tolerance
• Can cause addiction and withdrawal
• Interacts synergistically with other depressants
• Drowsiness
• Motor impairment
• Don’t use in a pt with major depression
• Decrease cognition

Question 15

What are the two sedative benzodiazepines?

Answer 15

• Diazepam (Valium)

- Alprazolam (Xanax)

Question 16

What is the half life of Diazepam (Valium)?

Answer 16

-20-100 hrs

Question 17

What is the half life of Alprazolam (Xanax)?

Answer 17

-6-12 hrs

Question 18

What are the two hypnotic benzodiazepines?

Answer 18

• Lorazepam (Ativan)

- Triazolam (Halcion)

Question 19

What is the half life of Triazolam?

Answer 19

• 2 hrs

Question 20

What is the half life of Lorazepam?

Answer 20

-6 hrs

Question 21

What is a benzo like sleep aid?

Answer 21

-Zolpidem (Ambien)

Question 22

What is the half life of zolpidem (Ambien)?

Answer 22

-2 hrs

Question 23

What do Barbiturates do?

Answer 23

-Enhance GABA

Question 24

What is a barbiturate that is used for short term anesthesia?

Answer 24

-Pentobarbital

Question 25

What is a barbiturates used for long-term seizures?

Answer 25

-Phenobarbital

Question 26

What do barbiturates have major interactions with?

Answer 26

• Liver

- Many drugs

Question 27

What is Propofol (Barbiturate) used for?

Answer 27

-General anesthesia

Question 28

What is a non sedative anxiolytic?

Answer 28

-Buspirone (BuSpar)

Question 29

What are the side effects of Buspirone (BuSpar)?

Answer 29

• Irregular heart beat

- Interacts with MAOi or antiseizure medicines

Question 30

What are indications to use Buspirone (BuSpar)?

Answer 30

• anxiety or tension associated with everyday stress

- If a person has co-existing depression with anxiety

Question 31

What symptoms do you see with Severe acute anxiety panic attacks?

Answer 31

-Increased sympathetic
-End up in the hospital because it seems like a Heart attack
-

Question 32

What are panic attacks treated with?

Answer 32

• Paxil

- Venlafaxin

Question 33

What is Paxil?

Answer 33

-An SSRI used to treat panic attacks

Question 34

What is Venlafaxin?

Answer 34

-An antidepressant with mixed effects to treat panic attacks

Question 35

What are phobic disorders?

Answer 35

-Irrational fears

Question 36

What is agoraphobia?

Answer 36

-Fear of space

Question 37

What drug do you use to treat phobic disorders?

Answer 37

-SSRIs such as Zoloft