Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Microbiology > T cell effector funcitons > Flashcards

T cell effector funcitons Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

Subsets of CD4+ helper T lymphocytes distinguished by_______ they produce

A

cytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

CD4+ helper T lymphocytes — Th1

A

INF y

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CD4+ helper T lymphocytes —- Th2

A

IL- 4,5,13

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CD4+ helper T lymphocytes —— Th17

A

IL- 17,22

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What cells to Th1 CD4+ helper T lymphocytes target?

A

macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What cells to Th2 CD4+ helper T lymphocytes target?

A

eosinophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What cells to Th17 CD4+ helper T lymphocytes target?

A

Neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the function of cytokine IL-2?

A

t cell proliferation; regulatory T cell survival.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the function of cytokine INF-y?

A

activation of macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the function of cytokine IL-4?

A

B cell switching to IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the function of cytokine IL-5?

A

activation of eosinophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the function of cytokine IL-17?

A

stimulation of acute inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the function of cytokine IL-22?

A

maintenance of epithelial barrier function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the function of cytokine TGF-b ?

A

inhibition of T cell activation; differentiation of regulatory T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Th1 cell function:

A

classical macrophage activation (enhanced microbial killing)

Three results:

Killing of phagocytosed bacteria

increased expression of MHC and costimulators (b7 molecules)

Secretion of cytokines (TNF, IL- 1, 12, cehmokines)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What induces Th2 cell function?

A

Induced by parasitic worm infections

17
Q

What are the signature cytokines of Th2 Cells.

A

IL-4, IL-5, IL-13

18
Q

What is the function of Th2 cells???

A

eosinophil activation

helminth death

19
Q

_______ _______ reactions are initiated by the introduction of an allergen, which stimulates TH2 reactions and immunoglobulin E (IgE) production

A

Immediate hypersensitivity

20
Q

T/F there is fluidity in the classes between Th1 and Th2 cells.

A

true

21
Q

T/F: In Th2 cell development IL-4 will allow the antigen activated T cell to autostimulate.

A

True

22
Q

What is the major function of Th17 cells?

A

Recruitment of neutrophils, resulting in inflammation

23
Q

_______ facilitates entry of granzymes into the cytosol, granzymes activate apoptosis.

A

Perforin

24
Q

What is the function of CD8+ cytotoxic T Lymphocytes

A
  1. bind to target cell
  2. become activated by target cell and release granules (granzymes)
  3. apoptosis of target cell.

Microbiology (46 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions