Antibiotic Quiz Flashcards
What is the class and the function of penicillin?
b-lactams
b-lactam antibiotics inhibit transpeptidation
What is the class and the function of vancomycin?
Glycoprotein
Binds to the D ala - D ala end of the peptidoglycan and inhibits crosslinking.
What is the class and the function of cephalonsporin?
b-lactams
b-lactam antibiotics inhibit transpeptidation
What is the class and the function of carbopenem?
b-lactams
b-lactam antibiotics inhibit transpeptidation
What is the class and the function of monobactams
b-lactams
b-lactam antibiotics inhibit transpeptidation
What is the class and the function of B-lactamase inhibitor?
b-lactams
this is not an antibiotic but rather a substance that prevents b lactamase from breaking down b lactam antibiotics
What is the class and the function of tiechoplanin?
glycoprotein
What is the class and the function of cyclloserine?
other membrane distruptor
Second line treatment for
My cobacterium tuberculosis
Cycloserine is a cyclic analog of alanine - Also crosses blood brain barrier and is an NMDA receptor agonist (with uses and side effects)
What is the class and the function of Ioniazid and ethionamide?
other membrane distruptor
Inhibits Mycobacteria by affecting synthesis of mycolic acid (abundant wax in the cell wall)
What is the class and the function of ethambutol?
other membrane distruptor
Inhibits Mycobacteria by affecting attachment of mycolic acid in the cell wall
What are the six antibiotics that deal with inhibiting amino acid synthesis?
oxizolidiones tetracylcine aminogylcosides chloramphenicol and lincosamides macrolides
What are the four antibiotics that are associated with inhibition of nucleic acid synthesis?
quinolones
rifampin
rifabutin
metronidazole
Drug Resistance: Penicillin and cephalosporins
plasmidborne
hydrolysis of beta lactam ring by beta lactamase
Drug Resistance: methicillin
no plasmidborne
change in penicllin binding protein
Drug Resistance: Tetracyclines
plasmid borne
efflux pump pushes drug out of cell
