Oral Bacteria B

Question 1

Pyogenic infections associated with the teeth and surrounding supporting structures

Answer 1

Dentoalveolar infections

Question 2

Endodontic infections are _______ infections that are opportunistic

Answer 2

endogenous

Question 3

Endodontic infections are endogenous infections that are _______

Answer 3

opportunistic

Question 4

•Spread from carious lesion
(1)•Tooth fracture/wear•Through periodontal membrane and accessory root canals
(2)
•Anachoresis(3) (via pulpal blood supply) during bacteremia from tooth extraction at different site

Answer 4

Dentoalveolar Abscess

Question 5

What are the 2 species of facultative anaerobes that are commonly isolated from dentoalveolar abscesses?

Answer 5

Strep sp

Actinomyces sp

Question 6

What are the 4 species of obligate anaerobes that are commonly isolated from dentoalveolar abscesses?

Answer 6

Peptostreptococcus spp
Porphyromonas gingivalis
Prevotella spp
Fusobacterium nucleatum

Question 7

A spreading, bilateral infection of the sublingual and submandibular spaces.Cellulitis of the fascial spaces rather than true abscess formation.
Mixed endogenous infection:Porphyromonas spp. Prevotella spp. Fusobacteria Anaerobic streptococci
-Airway obstruction is common

Answer 7

Ludwigs Angina

Question 8

What are the 2 most commonly cultivated bacterial species from root canal infections?

Answer 8

Bacteroides

Prevotella

Question 9

Localized collection of pus caused by acute or chronic destruction of periodontium Endogenous, subgingival plaque bacteria polymicrobial Porphyromonas spp. Prevotella spp. Fusobacteria Anaerobic streptococci

Answer 9

Periodontal abscess

Question 10

Porphyromonas spp. Prevotella spp. Fusobacteria Anaerobic streptococci but involves bone

Answer 10

Suppurative Osteomyelitis of the Jaws

Question 11

_____: endogenous, granulomatous disease
65% in cervicofacial region
Actinomyces (oral commensal)
visible granules in pus sulphur granules= collections of bacteria

Answer 11

Cervicofacial Actinomycosis

Question 12

_______
–congenital: Hutchinson’s incisors, mulberry molars
primary and secondary lesions
gummas (granulomatous lesions)

Answer 12

Syphilis

Question 13

_______

–oral lesions in up to 5% of primary and secondary causes ulcers on palate and gingiva

Answer 13

Tuberculosis

Question 14

For leprosy just know there are ____ oral manifestations

Answer 14

many

Question 15

Bacterial infections of salivary glands is often ______ species of bacteria

Answer 15

Staphylococcus

Question 16

What are the Diseases or situations associated with oral bacteria or their components?

Answer 16

Infective endocarditis
Disseminated intravascular coagulation
Nephritis
Rheumatoid arthritis
Behçets disease (chronic inflammatory disorder with oral ulcers)
Atherosclerosis
Low-birth-weight infants

Question 17

Microbial ____ are very similar to human that are normally shielded within cells. Antibodies elicited by bacterial ____ can cross-reactwith exposed human HSPs (e.g. present in damaged tissue). If immune complexes are deposited in the arterial wall (atherosclerosis), joints (arthritis), or mucous membranes (Behçets disease), its mimicrycan contribute to systemic disease.

Answer 17

Heat shock proteins

Question 18

Streptococcus sanguinis express an epitope within PAAP (platelet-aggregation associated protein), which is similar to the arthritogenic epitope of type II collagen. In a murine arthritis model, S. sanguinis infection exacerbates arthritis.Interestingly, exposure of neonatal mice to PAAP+S. sanguinis inhibited development of autoimmune arthritis in the adult (early exposure protective?).

Answer 18

Autorecognition induced by oral microorganisms

Question 19

_______ portion of the oral surfaces:

Contains TLRs: TLRs recognize PAMPs(Pathogen-Associated Molecular Patterns)

Answer 19

The mucosal barrier

Question 20

Small peptides (proteins) that form pores in bacterial membranes, disrupting cells.
HBD-1 (human b-defensin 1) is the main one produced by epithelial cells.
Bacterial membranes are susceptible due to their high phospholipid content.

Answer 20

Defensins

Question 21

_______ is the main defensin produced by epithelial cells.

Answer 21

HBD-1 (human b-defensin 1)

Question 22

Mucins attached to mucosal surface form a selectively permeable layer (a mucus coat analogous to a bacterial capsule).
Mucins are glycoproteins and carbo-hydrates portion form a sticky slippery gel.
MG1and MG2 are mucins in oral cavity.

Answer 22

Adherent mucin layer

Question 23

Endogenous bacteria keep out new bacteria, and the stimulate immune system. But they can cause disease when the balance shifts.

Answer 23

Commensal oral microbiota

Question 24

How much saliva is secreted into the mouth per day?

Answer 24

.5-1.5L

Question 25

MG1 and MG2 aggregate and clear oral microbes via lectin-like interactions.

Answer 25

Mucins

Question 26

Degrades peptidoglycan by cutting bond between NAG and NAM (muramidase)

Answer 26

Lysozyme