Self Study NC's for weeks 1-2 Flashcards
Carries preganglionic sympathetic axons
White rami
Carries postganglionic sympathetic axons that are distributed to somatic structures
Gray rami
Sensory neurons coming back to the spinal cord move from the paravertebral ganglia to the ventral rami via
White rami communicans
The spinal nerve arising from the conus medularis
Coccygeal nerve
Thin filament at the end of the conus medularis
Filum terminale
How many different types of channels (isoforms) are allowing the plateau potential?
5
What is phase 0 of a plateau potential?
Rapid depolarization due to voltage-gated Na+ channel
What is phase 1 of a plateau potential?
Transient repolarization due to opening of K+ channel
What is phase 2 of a plateau potential?
The plateau phase (both Ca2+ and a different K+ channels are open)
What is phase 3 of a plateau potential?
Another K+ channel opens and we see repolarization
What is phase 4 of a plateau potential?
Refraction
ACh receptor antagonists
α-toxins
Botulinus and tetanus block
ACh release
Blocks neuronal and cardiac voltage-gated Na+ channels
Tetrodotoxin
Blocks motor neuron voltage-gated K+ channels
Dendrotoxin
Making the RMP more negative has what effect?
Inhibits AP generation
Making the RMP more positive has what effect?
Stimulates AP generation
Synaptic transmission that functions through stimulation of ligand-gated ion channels
Ionotropic transmission
Synaptic transmission that functions through ligand-receptor binding to initiate intracellular signalling cascades which will then activate ion channels
Metabotropic transmission
The SA node exhibits
Metabotropic transmission
In the SA node, blocking ACh binding to its receptor would have what effect?
Prevent efflux of K+, making it harder to reach threshold
The neurotransmitter in the parasympathetic nervous system that slows heart rate
ACh
