Cranial Meninges and Intracranial Circulation Flashcards
Within the cranial cavity, the dura matter is composed of which two layers?
Periosteal dura, and meningeal dura
Lines the inner surface of the skull and serves as the periosteum (Endosteum)
PEriosteal Dura
There is normally no space between the periosteal dura and the bone of the skull. However under abnormal circumstances (i.e. bleeding) A space is created there called the
Epidural (or extradural) space
The meningeal dura is fused to the periosteal dura for much of its surface, but in some regions it separates from the periosteal dura to turn internally to form
Dural Septa
The major dural septa include the
Falx cerebri, Falx cerebelli, and Tentorium cerebelli
The Falx cerebri, Falx cerebelli, and Tentorium cerebelli are all composed of only
Meningeal dura
Lies between the two cerebral hemispheres
Falx cerebri
Lies between the two cerebellar hemispheres
Falx ceribelli
Lies between the cerebellum and the occipital lobe of the cerebrum
Tentorium cerebelli
Lie between periosteal dura and the meningeal dura in the regions where the two layers separate
Dural Venous sinuses
Dural venous sinuses are also found within reflections of the
Meningeal dura
Dural sinuses are lined with the same epithelium that is found lining the
Veins of the body
Lies between the periosteal dura and meningeal dura at the root of the falx cerebri
Superior saggital sinus
Lies within a reflection of the meningeal dura at the free edge of the falx cerebri
Inferior saggital sinus
Lies between periosteal dura and meningeal dura at the root of the falx cerebelli
Occipital sinus
Lies within
meningeal dura at the intersection of the falx cerebri and tentorium cerebelli
Straight sinus
Located between periosteal and meningeal dura at the point where the superior sagittal, occipital and straight
sinuses meet
Confluens of sinuses
Lies between periosteal and meningeal dura at the attachment of the
tentorium cerebelli
Transverse sinuses
The anterior continuation of the transverse sinuses
-Drains into the jugular bulb
Sigmoid sinuses
Lie between periosteal and meningeal dura forming the lateral walls of the pituitary fossa`
Cavernous sinuses
Connects the cavernous sinus to the sigmoid sinus
Superior petrosal sinuses
Drains the cavernous sinus into the jugular bulb
Inferior petrosal sinuses
Carry most of the venous drainage from the brain
Dural sinuses
The dural sinuses drain into the
Internal jugular vein
The dural sinuses drain into the internal jugular vein and also communicate with veins of the face, scalp, and neck through
Emissary veins
Do not contain valves
Emissary veins
Since emissary veins do not contain valves, blood can flow in either direction. Thus, these veins can be pathways for the
Spread of infection from superficial regions of the face and scalp into the cranial cavity
Intimately fused to the brain
-Follows the sulci and gyri of the cerebral cortex
Pia matter
Does not enter the sulci. It is adherent to the inner surface of the meningeal dura
Arachnoid matter
Are the dura and arachnoid surfaces fused together?
No
The arachnoid is pressed against the dura by
Cerebrospinal fluid pressure
There is usually no space between the
Dura and arachnoid
Highly vascularized tissue found in the ventricles of the brain
-Secrete cerebrospinal fluid
Choroid plexuses
The upward continuations of the central canal of the spinal cord
Ventricles of the brain
How many ventricles of the brain are there
Four: two lateral, the midline third, and midline fourth ventricles
The midline third ventricle is located in the
Diencephalon
The midline fourth ventricle is located
Between the cerebellum and pons and the medulla
CSF produced in the lateral ventricles enters the third ventricle through the
Interventricular foramina (of Monro)
From the third ventricle, CSF passes to the fourth ventricle through the
Cerebral aqueduct (of Sylvius)
-In the midbrain
From the fourth ventricle, CSF may continue into the central canal, but mostly it enters the
Subarachnoid space
CSF enters the subarachnoid space from the 4th ventricle through which three openings?
2 Lateral foramina (of Luschka) and 1 MEdian foramen (of Magendie)
CSF is resorbed into the venous system at the
Arachnoid granulations
Tufts of arachnoid that come into close contact with thinned out regions of the dural wall of the superior saggital sinus
Arachnoid granulations
Approximately how much CSF is there in the subarachnoid space and ventricles at any one time?
125-150 mL
How much CSF is secreted in the average adult each day?
450 - 500 mL
CSF in the subarachnoid space normally has a pressure of bout
80-120 mmH20
An abnormal increase in intracranial CSF pressure results in
Hydrocephalus
What are the two major categories of hydrocephalus?
- ) Communicating hydrocephalus
2. ) Non-communicating (or obstructive) hydrocephalus
CSF is able to pass from the ventricles to the subarachnoid space, but resorption into the venou ssystem does not keep pace with CSF production
Communicating hydrocephalus
CSF produced in the ventricles is obstructed in its passage to the subarachnoid space and thus there is diminished resorption into the venous system
Non-communicating (obstructive) Hydrocephalus
Communicating hydrocephalus is usually caused by a defect in
Resorption
Non-communicating hydrocephalus is most commonly caused by
Narrowing of the cerebral aqueduct
Non-communicating hydrocephalus is less commonly caused by an obstruction in the
Lateral and/or median foramina or the interventricular foramen
The brain receives its blood supply from
2 vertebral and 2 internal carotid arteries
The vertebral arteries supply mostly the
Brainstem, cerebellum, and occipital lobe of the cerebrum
Supply most of the remainder of the brain
Internal carotid arteries
These 4 arteries anastomose with eachother to form the
Cerebral arterial circle (CIrcle of Willis)
At the pons-medulla junction, the two vertebral arteries join to form the
Basilar artery
At the pons-midbrain junction, the basilar artery divides into
2 Posterior cerebral arteries
After exiting from the cavernous sinus, the internal carotid artery divides into the
Anterior cerebral artery, middle cerebral artery, and posterior communicating artery
Connect the two internal carotid arteries to the two posterior cerebral arteries
Right and left posterior communicating arteries
The two anterior cerebral arteries are connected by the
-forms the communication between right and left carotid system
Anterior communicating artery
The cerebral arteries are bound to the pia matter and therefore are in the
Subarachnoid space
The middle meningeal artery (branch of the maxillary artery) enters the cranial cavity through the
Foramen spinosum
Within the cranial cavity, branches of the middle meningeal artery lie between the
Inner surface of the skull and periosteal dura (tightly bound to the dura)
These branches may be injured by trauma to the overlying skull resulting in arterial bleeding into the plane between the periosteal dura and the skull. This is called an
Epidural hematoma
What is the most common sight of injury for an epidural hematoma?
Lateral side of the head in the region of the pterion
Patients with an epidural hematoma will often have a period of time known as the
Lucid interval
During this lucid period, the size of the hematoma is increasing until the increased cranial pressure again causes
Unconsciousness
The cortex of the brain has venous drainage through cortical veins which drain into dural venous sinuses, primarily the
Superior saggital sinus
These veins “bridge” across the subarachnoid space to penetrate the arachnoid and then the
Dura
Tearing of these bridging veins by force or rapid deceleration at the site where they are anchored to the dura results in a
Subdural hematoma
-Separates arachnoid and dura creating subdural space
Onset of a subdural hematoma is slower than an epidural hematoma because of the
Slower leaking blood from lower pressure veins
Because the periosteal dura is very tightly attached to the bone of the skull at the suture lines, what type of hematoma does not cross suture lines?
Epidural hematoma
Can cross suture lines
-Allows clinicians to differentiate between types of hematoma on imaging
Subdural hematoma
The arteries that provide blood supply to the brain are bound in the pia matter on the surface of the brain and thus are in the
Subarachnoid space
Rupture of any of these arteries as a ruptured cerebral aneurysm or head trauma will result in a
Subarachnoid hemorrhage
In a subarachnoid hemorrhage, arterial blood enters the subarachnoid space and mixes with
CSF
How can a subarachnoid hemorrhage be diagnosed?
By presence of blood in CSF in a spinal tap
What are some symptoms of a subarachnoid hemorrhage?
Severe rapid onset headache (worst of life), and may have vomitin, seziures, disorientaton or other neurological signs/symptoms