SCHIZO BIO EVAL - neural Flashcards

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1
Q

DOPMAINE HYPOTHESIS LIMITATION - Explanation/Evidence

LIMITATION of the dopmaine hypothesis is x for teh x x of x

x x and x x x consitlently found raised level of x glutamate in x x regions of people with x

in addtiiton several x x for schizo are believed to be involved in glutamate x or x

this means that an x strong case can be made for the x of other xx

A

LIMITATION of the dopmaine hypothesis is evidence for teh central role of glutamte

post mortem and live scannigns tudies consitlently found raised level so fneurtotransmitter glutamate in several brain regions of people with schizophrenia

in addtiiton several candidate genes for schizo are believed to be involved in glutamate production or processing

this means that an equally strong case can be made for the role of other NT

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2
Q

strength - dopmaine hypothesis - evidence from drug studies

there is support from a number of x for x dopamine funcitonng in schizophrenia

dopmaine x like x that x teh levels of x makes schizophrenia x and can produce schizophrenia like symptoms in x x

x drugs on the other hand work by x dopamine activity and are used x with many x patients

furthermore research has suggested a x of candidate genes x in schizophrenia act on the x of x OR ON x x

All of this x suggests that x is involved in the x of schizophrenia

A

there is support from a number of sources for abnormal dopamine funcitonng in schizophrenia

dopmaine anotginiss like amphetamines that increase teh levels of dopmaine makes schizophrenia worse and can produce schizophrenia like symptoms in non sufferers

antipsychotic drigs on the other hand work by reducing dopamine activity and are used effectivley with many schizophrenic patients

furthermore reserch has suggested a number of candidate genes implicated in schizophrenia act on the produciton of DOPMAINE OR ON DOPAMINE RECEPTORS

All of this strngly suggests that dopamine is involved in the symptoms of schizophrenia

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3
Q

bio determinism point

clear evidence to show that x factors also increase x of developing schizo

these enviro factors also icnlude x and x influences

biological risk fctors include x x (MORGAN ET AL ) and smoking xxx x x in x years

psycho risk factors include x which leaves people more x to adult mental health problems in general but now evidence for x link with schizo

study by x et al found x% people with schizo and related psychotic conditions reported at least x childhood trauma as opposed to x% of x group with non x mental health problems

this means x factors alone cannot provide a complete explanatino for schizophrenia

A

clear evidence to show that enviro factors also increase risk of developing schizo

these enviro factors also icnlude bio and psyc influences

biological risk fctors include birth compications (MORGAN ET AL ) and smoking THC rich cannabis in teen years

psycho risk factors include childhood trauma which leaves people more vulnerable to adult mental health problems in general but now evidence for ptclr link with schizo

study by Mokved et al found 67% people with schizo and related psychotic conditions reported at least one childhood trauma as opposed to 38% of match group with non psychotic mental health problems

this means neural factors alone cannot provide a complete explanatino for schizophrenia

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